TSPO ligand-2

Modify Date: 2025-09-11 17:11:05

TSPO ligand-2 Structure
TSPO ligand-2 structure
Common Name TSPO ligand-2
CAS Number 1160640-95-8 Molecular Weight 447.48
Density N/A Boiling Point N/A
Molecular Formula C23H29NO8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TSPO ligand-2


TSPO ligand-2 is a ligand of AUTAC1. AUTAC1 contains an p-fluorobenzylguanine (FBnG) and a Fumagillol moiety, which can silence endogenous MetAP2 in HeLa cells[1].

 Names

Name TSPO ligand-2

 TSPO ligand-2 Biological Activity

Description TSPO ligand-2 is a ligand of AUTAC1. AUTAC1 contains an p-fluorobenzylguanine (FBnG) and a Fumagillol moiety, which can silence endogenous MetAP2 in HeLa cells[1].
Related Catalog
References

[1]. Takahashi D, et al. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76(5):797-810.e10.

 Chemical & Physical Properties

Molecular Formula C23H29NO8
Molecular Weight 447.48
InChIKey APRLZHSZVREOFG-HUCDYXQFSA-N
SMILES COC1C(OC(=O)Oc2ccc([N+](=O)[O-])cc2)CCC2(CO2)C1C1(C)OC1CC=C(C)C
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