3-Cyanovinylcarbazole phosphoramidite

Modify Date: 2025-08-21 07:56:23

3-Cyanovinylcarbazole phosphoramidite Structure
3-Cyanovinylcarbazole phosphoramidite structure
Common Name 3-Cyanovinylcarbazole phosphoramidite
CAS Number 1157899-72-3 Molecular Weight 836.95300
Density N/A Boiling Point N/A
Molecular Formula C50H53N4O6P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3-Cyanovinylcarbazole phosphoramidite


3-Cyanovinylcarbazole phosphoramidite is an antiviral drug that inhibits the synthesis of viral DNA. The modified nucleoside in the compound is synthesized by modifying the ribonucleotide with cyano group at the C-3 position, and can be used as a phosphoric acid amide for DNA synthesis[1].

 Names

Name 5'-O-(4,4'-dimethoxytrityl)-3-cyanovinylcarbazole-1'-β-deoxyriboside-3'-O-(cyanoethoxy-N,N-diisopropylamino)phosphoramidite
Synonym More Synonyms

 3-Cyanovinylcarbazole phosphoramidite Biological Activity

Description 3-Cyanovinylcarbazole phosphoramidite is an antiviral drug that inhibits the synthesis of viral DNA. The modified nucleoside in the compound is synthesized by modifying the ribonucleotide with cyano group at the C-3 position, and can be used as a phosphoric acid amide for DNA synthesis[1].
Related Catalog
References

[1]. Takashi Sakamoto, et al. DNA photo-cross-linking using 3-cyanovinylcarbazole modified oligonucleotide with threoninol linker. Org Lett. 2015 Feb 20;17(4):936-9.   

 Chemical & Physical Properties

Molecular Formula C50H53N4O6P
Molecular Weight 836.95300
Exact Mass 836.37000
PSA 124.72000
LogP 11.30590
InChIKey NLRMEFDNJQEAHT-UHFFFAOYSA-N
SMILES C=Cc1cc(C#N)cc2c1[nH]c1ccccc12.NP(O)O

 Synonyms

3-cyanovinylcarbazole phosphoramidite
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