3-Cyanovinylcarbazole phosphoramidite

Names

[ Name ]:
3-Cyanovinylcarbazole phosphoramidite

[Synonym ]:
3-cyanovinylcarbazole phosphoramidite

Biological Activity

[Description]:

3-Cyanovinylcarbazole phosphoramidite is an antiviral drug that inhibits the synthesis of viral DNA. The modified nucleoside in the compound is synthesized by modifying the ribonucleotide with cyano group at the C-3 position, and can be used as a phosphoric acid amide for DNA synthesis[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

[References]

[1]. Takashi Sakamoto, et al. DNA photo-cross-linking using 3-cyanovinylcarbazole modified oligonucleotide with threoninol linker. Org Lett. 2015 Feb 20;17(4):936-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₀H₅₃N₄O₆P

[ Molecular Weight ]:
836.95300

[ Exact Mass ]:
836.37000

[ PSA ]:
124.72000

[ LogP ]:
11.30590

Related Compounds

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