2-Chloro-N-[(6-{[3-(4-methyl-1-piperazinyl)propyl]sulfonyl}-1,3-benzothiazol-2-yl)carbamoyl]-5-(4-morpholinyl)benzamide

Modify Date: 2024-01-06 12:15:38

2-Chloro-N-[(6-{[3-(4-methyl-1-piperazinyl)propyl]sulfonyl}-1,3-benzothiazol-2-yl)carbamoyl]-5-(4-morpholinyl)benzamide Structure
2-Chloro-N-[(6-{[3-(4-methyl-1-piperazinyl)propyl]sulfonyl}-1,3-benzothiazol-2-yl)carbamoyl]-5-(4-morpholinyl)benzamide structure
 Common Name 2-Chloro-N-[(6-{[3-(4-methyl-1-piperazinyl)propyl]sulfonyl}-1,3-benzothiazol-2-yl)carbamoyl]-5-(4-morpholinyl)benzamide
CAS Number 1143020-91-0 Molecular Weight 621.171
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C27H33ClN6O5S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-Chloro-N-[(6-{[3-(4-methyl-1-piperazinyl)propyl]sulfonyl}-1,3-benzothiazol-2-yl)carbamoyl]-5-(4-morpholinyl)benzamide


AZ-GHS-22 is a potent, non-CNS penetrant GHS-R1a inverse agonist (IC50=0.77 nM)[1].

 Names

Name 2-Chloro-N-[(6-{[3-(4-methyl-1-piperazinyl)propyl]sulfonyl}-1,3-benzothiazol-2-yl)carbamoyl]-5-(4-morpholinyl)benzamide
Synonym More Synonyms

  Biological Activity

Description AZ-GHS-22 is a potent, non-CNS penetrant GHS-R1a inverse agonist (IC50=0.77 nM)[1].
Related Catalog
References

[1]. McCoull W, et al. Identification, optimization, and pharmacology of acylurea GHS-R1a inverse agonists. J Med Chem. 2014;57(14):6128-6140.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C27H33ClN6O5S2
Molecular Weight 621.171
Exact Mass 620.164246
LogP 0.61
Index of Refraction 1.645

 Synonyms

Benzamide, 2-chloro-N-[[[6-[[3-(4-methyl-1-piperazinyl)propyl]sulfonyl]-2-benzothiazolyl]amino]carbonyl]-5-(4-morpholinyl)-
2-Chloro-N-[(6-{[3-(4-methyl-1-piperazinyl)propyl]sulfonyl}-1,3-benzothiazol-2-yl)carbamoyl]-5-(4-morpholinyl)benzamide
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Chemsrc provides CAS#:1143020-91-0 MSDS, density, melting point, boiling point, structure, etc. Its name is 2-Chloro-N-[(6-{[3-(4-methyl-1-piperazinyl)propyl]sulfonyl}-1,3-benzothiazol-2-yl)carbamoyl]-5-(4-morpholinyl)benzamide>> amp version: 2-Chloro-N-[(6-{[3-(4-methyl-1-piperazinyl)propyl]sulfonyl}-1,3-benzothiazol-2-yl)carbamoyl]-5-(4-morpholinyl)benzamide

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