1143020-91-0

1143020-91-0 structure

Name: 2-Chloro-N-[(6-{[3-(4-methyl-1-piperazinyl)propyl]sulfonyl}-1,3-benzothiazol-2-yl)carbamoyl]-5-(4-morpholinyl)benzamide
Chemical Name: 2-Chloro-N-[(6-{[3-(4-methyl-1-piperazinyl)propyl]sulfonyl}-1,3-benzothiazol-2-yl)carbamoyl]-5-(4-morpholinyl)benzamide
CAS Number: 1143020-91-0
Molecular Formula: C₂₇H₃₃ClN₆O₅S₂
Molecular Weight: 621.171
Catalog: Signaling Pathways GPCR/G Protein GHSR
Create Date: 2018-06-09 16:08:17
Modify Date: 2024-01-06 12:15:38
AZ-GHS-22 is a potent, non-CNS penetrant GHS-R1a inverse agonist (IC50=0.77 nM)[1].

Name	2-Chloro-N-[(6-{[3-(4-methyl-1-piperazinyl)propyl]sulfonyl}-1,3-benzothiazol-2-yl)carbamoyl]-5-(4-morpholinyl)benzamide
Synonyms	Benzamide, 2-chloro-N-[[[6-[[3-(4-methyl-1-piperazinyl)propyl]sulfonyl]-2-benzothiazolyl]amino]carbonyl]-5-(4-morpholinyl)- 2-Chloro-N-[(6-{[3-(4-methyl-1-piperazinyl)propyl]sulfonyl}-1,3-benzothiazol-2-yl)carbamoyl]-5-(4-morpholinyl)benzamide

Description	AZ-GHS-22 is a potent, non-CNS penetrant GHS-R1a inverse agonist (IC50=0.77 nM)[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> GHSR
References	[1]. McCoull W, et al. Identification, optimization, and pharmacology of acylurea GHS-R1a inverse agonists. J Med Chem. 2014;57(14):6128-6140.