nor-NOHA acetate

Modify Date: 2024-01-09 10:00:40

nor-NOHA acetate Structure
nor-NOHA acetate structure
Common Name nor-NOHA acetate
CAS Number 1140844-63-8 Molecular Weight 296.28
Density N/A Boiling Point N/A
Molecular Formula C9H20N4O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of nor-NOHA acetate


nor-NOHA acetate is a specific and reversible arginase inhibitor, induces apoptosis in ARG2-expressing cells under hypoxia but not normoxia. Anti-leukemic activity, effective in endothelial dysfunction, immunosuppression and metabolism[1].

 Names

Name nor-NOHA acetate

 nor-NOHA acetate Biological Activity

Description nor-NOHA acetate is a specific and reversible arginase inhibitor, induces apoptosis in ARG2-expressing cells under hypoxia but not normoxia. Anti-leukemic activity, effective in endothelial dysfunction, immunosuppression and metabolism[1].
Related Catalog
Target

Arginase[1]

References

[1]. Ng KP, et al. The arginase inhibitor Nω-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target. PLoS One. 2018 Oct 11;13(10):e0205254.

 Chemical & Physical Properties

Molecular Formula C9H20N4O7
Molecular Weight 296.28
Storage condition 2-8℃