MK-0941
Modify Date: 2025-08-22 11:45:44
MK-0941 structure
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Common Name | MK-0941 | ||
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| CAS Number | 1137916-97-2 | Molecular Weight | 556.60900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H28N4O9S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MK-0941MK-0941 is a potent, orally active and allosteric glucokinase activator, with EC50s of 240 and 65 nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 has potential in the treatment of type 2 diabetes[1]. |
| Name | 3-(6-ethanesulfonylpyridin-3-yloxy)-5-((S)-2-hydroxy-1-methylethoxy)-N-(1-methyl-1H-pyrazol-3-yl)benzamide methanesulfonic acid salt |
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| Synonym | More Synonyms |
| Description | MK-0941 is a potent, orally active and allosteric glucokinase activator, with EC50s of 240 and 65 nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 has potential in the treatment of type 2 diabetes[1]. |
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| Related Catalog | |
| Target |
EC50: 240 nM (Recombinant human glucokinase, 2.5 mM glucose), 65 nM (Recombinant human glucokinase, 10 mM glucose)[1] |
| References |
| Molecular Formula | C22H28N4O9S2 |
|---|---|
| Molecular Weight | 556.60900 |
| Exact Mass | 556.13000 |
| PSA | 203.77000 |
| LogP | 4.15150 |
| InChIKey | PIDNRTWDGDJKSQ-UQKRIMTDSA-N |
| SMILES | CCS(=O)(=O)c1ccc(Oc2cc(OC(C)CO)cc(C(=O)Nc3ccn(C)n3)c2)cn1.CS(=O)(=O)O |
| Storage condition | -20℃ |
| 3-(6-ethanesulfonylpyridin-3-yloxy)-5-((1S)-2-hydroxy-1-methyl-ethoxy)-N-(1-methyl-1H-pyrazol-3-yl)benzamide methanesulfonate |
| MK-0941 |