AWL-II-38.3

Modify Date: 2025-08-26 13:53:51

AWL-II-38.3 Structure
AWL-II-38.3 structure
 Common Name AWL-II-38.3
CAS Number 1135205-94-5 Molecular Weight 469.42
Density N/A Boiling Point N/A
Molecular Formula C23H18F3N5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AWL-II-38.3


AWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. AWL-II-38.3 does not exhibit significant cellular activity against Src-family kinases nor against b-raf[1][2][1][2].

 Names

Name AWL-II-38.3

 AWL-II-38.3 Biological Activity

Description AWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. AWL-II-38.3 does not exhibit significant cellular activity against Src-family kinases nor against b-raf[1][2][1][2].
Related Catalog
Target

Ephrin-A receptor (EphA3) kinase[1][2]

In Vitro AWL-II-38.3 fits to LIMK2 and LIMK1 ATP-binding and substrate-binding pockets[2].
References

[1]. Yongmun Choi, et al. Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4467-70.

[2]. Efrat Mashiach-Farkash, et al. Computer-based identification of a novel LIMK1/2 inhibitor that synergizes with salirasib to destabilize the actin cytoskeleton. Oncotarget. 2012 Jun;3(6):629-39.

 Chemical & Physical Properties

Molecular Formula C23H18F3N5O3
Molecular Weight 469.42
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Chemsrc provides AWL-II-38.3(CAS#:1135205-94-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of AWL-II-38.3 are included as well.>> amp version: AWL-II-38.3

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