ondansetron-d3

Modify Date: 2024-01-02 15:56:07

ondansetron-d3 structure	Common Name	ondansetron-d3
	CAS Number	1132757-82-4	Molecular Weight	296.38100
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₆D₃N₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ondansetron-d3

Ondansetron-d3 is the deuterium labeled Ondansetron[1]. Ondansetron(GR 38032;SN 307) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy[2].

Name	ondansetron-d3

Description	Ondansetron-d3 is the deuterium labeled Ondansetron[1]. Ondansetron(GR 38032;SN 307) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy[2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Brown AM, et al. Ion permeation and conduction in a human recombinant 5-HT3 receptor subunit (h5-HT3A). J Physiol. 1998 Mar 15;507 ( Pt 3):653-65.

Molecular Formula	C₁₈H₁₆D₃N₃O
Molecular Weight	296.38100
Exact Mass	296.17200
PSA	39.82000
LogP	3.12850

ondansetron-d3

Use of ondansetron-d3

Names

ondansetron-d3 Biological Activity

Chemical & Physical Properties