PD128907 HCl
Modify Date: 2024-01-27 20:03:14
PD128907 HCl structure
|
Common Name | PD128907 HCl | ||
|---|---|---|---|---|
| CAS Number | 112960-16-4 | Molecular Weight | 285.77 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H20ClNO3 | Melting Point | 145-153°C | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of PD128907 HClPD 128907 (hydrochloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
| Name | (4aR,10bR)-4-propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-ol,hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | PD 128907 (hydrochloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
|---|---|
| Related Catalog | |
| In Vitro | PD128907 hydrochloride 是一种有效的选择性多巴胺 D3 受体激动剂，EC50 为 0.64 nM，比多巴胺 D2 受体选择性高 53 倍。 |
| Melting Point | 145-153°C |
|---|---|
| Molecular Formula | C14H20ClNO3 |
| Molecular Weight | 285.77 |
| Exact Mass | 285.11300 |
| PSA | 41.93000 |
| LogP | 2.67640 |
| Appearance of Characters | white |
| Storage condition | 2-8°C |
| Water Solubility | H2O: >5mg/mL |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
|
Neurochemical and functional characterization of the preferentially selective dopamine D3 agonist PD 128907.
J. Pharmacol. Exp. Ther. 275 , 1355, (1995) The present study determined the biochemical and pharmacological effects of PD 128907 [R-(+)-trans-3,4,4a,10b-tetrahydro-4-propyl-2H,5H- [1]benzopyrano[4,3-b]-1,4-oxazin-9-ol], a dopamine (DA) recepto... |
|
|
Synthesis and dopamine agonist properties of (+-)-trans-3,4,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano [4,3-b]-1,4-oxazin-9-ol and its enantiomers.
J. Med. Chem. 33 , 445-450, (1990) The dopamine agonist profile of (+-)-trans-3,4,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano [4,3-b]-1,4-oxazin-9-ol (16a) and its enantiomers (16b-c) was examined. Racemic 16a exhibited moderate af... |
|
|
Dopamine D3 (auto) receptors inhibit dopamine release in the frontal cortex of freely moving rats in vivo.
J. Neurochem. 66 , 2209, (1996) In freely moving rats, the novel, selective dopamine (DA) D3 receptor agonist PD 128,907 dose-dependently [effective dose (ED25) = 0.07 mg/kg, s.c.] reduced dialysate levels of DA in the frontal corte... |
| (+)-(4aR,10bR)-3,4,4a,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol hydrochloride |
| S(+)-PD 128,907 hydrochloride |
| PD 125,530 |
| R(-)-PD 128,908 hydrochloride |
| S(+)-(4aR,10bR)-3,4,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol hydrochloride |
| (+)-PD 128,907 hydrochloride |