CM398

Modify Date: 2024-01-11 07:02:46

CM398 Structure
CM398 structure
Common Name CM398
CAS Number 1121931-70-1 Molecular Weight 395.49
Density N/A Boiling Point N/A
Molecular Formula C23H29N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CM398


CM398 is a highly selective, orally active sigma-2 receptor ligand (Ki=0.43 nM), with high sigma-1/sigma-2 selectivity rato (1000-fold). CM398 shows notable affinity for dopamine (Ki=32.90 nM) and serotonin transporters (Ki=244.2 nM). CM398 shows promising anti-inflammatory analgesic effects in the formalin model of inflammatory pain in mice[1].

 Names

Name CM398

 CM398 Biological Activity

Description CM398 is a highly selective, orally active sigma-2 receptor ligand (Ki=0.43 nM), with high sigma-1/sigma-2 selectivity rato (1000-fold). CM398 shows notable affinity for dopamine (Ki=32.90 nM) and serotonin transporters (Ki=244.2 nM). CM398 shows promising anti-inflammatory analgesic effects in the formalin model of inflammatory pain in mice[1].
Related Catalog
References

[1]. Intagliata S, et al. Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In Vivo. AAPS J. 2020;22(5):94. Published 2020 Jul 20.

 Chemical & Physical Properties

Molecular Formula C23H29N3O3
Molecular Weight 395.49
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  • China
  • Product Name: CM398
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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