Triethylene glycol dimethyl ether

Modify Date: 2025-08-21 11:05:08

Triethylene glycol dimethyl ether structure	Common Name	Triethylene glycol dimethyl ether
	CAS Number	112-49-2	Molecular Weight	178.22600
	Density	0.986 g/mL at 25 °C(lit.)	Boiling Point	216 °C(lit.)
	Molecular Formula	C₈H₁₈O₄	Melting Point	−45 °C(lit.)
	MSDS	Chinese USA	Flash Point	231 °F
	Symbol	GHS07, GHS08	Signal Word	Danger

Name	triglyme
Synonym	More Synonyms

Density	0.986 g/mL at 25 °C(lit.)
Boiling Point	216 °C(lit.)
Melting Point	−45 °C(lit.)
Molecular Formula	C₈H₁₈O₄
Molecular Weight	178.22600
Flash Point	231 °F
Exact Mass	178.12100
PSA	36.92000
LogP	0.31240
Vapour density	>4.7 (vs air)
Index of Refraction	n20/D 1.423(lit.)
Storage condition	Refrigerator

Triethylene glycol dimethyl ether MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XF0665000

CHEMICAL NAME :: 2,5,8,11-Tetraoxadodecane

CAS REGISTRY NUMBER :: 112-49-2

BEILSTEIN REFERENCE NO. :: 1700630

LAST UPDATED :: 199710

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C8-H18-O4

MOLECULAR WEIGHT :: 178.26

WISWESSER LINE NOTATION :: 1O2O2O2O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 7500 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB86-103215

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 5 gm/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 31,53A,1985

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 7500 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - uterus, cervix, vagina

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB86-103215

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 28 gm/kg

SEX/DURATION :: female 6-13 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)

REFERENCE :: TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980- Volume(issue)/page/year: 7,29,1987

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 3500 mg/kg

SEX/DURATION :: female 6-19 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB87-181657

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 3500 mg/kg

SEX/DURATION :: female 6-19 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Effects on Embryo or Fetus - fetal death

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB87-181657

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 3325 mg/kg

SEX/DURATION :: female 6-19 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 19,238,1992 *** REVIEWS *** TOXICOLOGY REVIEW FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 13,747,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - E0064 No. of Facilities: 27 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 270 (estimated)

Symbol	GHS07, GHS08
Signal Word	Danger
Hazard Statements	H319-H360Df
Supplemental HS	May form explosive peroxides.
Precautionary Statements	P201-P280-P305 + P351 + P338-P308 + P313-P337 + P313
Hazard Codes	T:Toxic;
Risk Phrases	R19;R61;R62
Safety Phrases	S53-S45
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	XF0665000
HS Code	2942000000

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HS Code	2901100000
Summary	2901100000 saturated acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

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Dimethyltriglycol

EINECS 203-977-3

Triethylene glycol dimethyl ether

MFCD00008504

1,2-Bis(2-methoxyethoxy)ethane,Dimethyltriglycol,Triglyme

2,5,8,11-Tetraoxadodecane

1-methoxy-2-[2-(2-methoxyethoxy)ethoxy]ethane

1,2-Bis(2-methoxyethoxy)ethane

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Henan Tianfu Chemical Co., Ltd.
China
Product Name: triglyme
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China
Product Name: Triethylene glycol dimethyl ether
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Triethylene glycol dimethyl ether

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