AZD5213

Modify Date: 2024-01-02 10:37:10

AZD5213 structure	Common Name	AZD5213
	CAS Number	1119807-02-1	Molecular Weight	327.42
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₂₅N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AZD5213

AZD5213 is a selective and competitive human H3 receptor antagonist with a pKi value of 9.3 for hH3R. AZD5213 can be used for the research of sleep and cognitive regulation[1][2].

Name	AZD5213

Description	AZD5213 is a selective and competitive human H3 receptor antagonist with a pKi value of 9.3 for hH3R. AZD5213 can be used for the research of sleep and cognitive regulation[1][2].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
In Vivo	AZD5213 (1 mg/kg；静脉注射一次) 迅速减少 [11C] 4-(1S,2S)-2-(4-cyclobutylpiperazine-1-carbonyl)-cyclopropyl]-N-methyl-benzamide 与小鼠大脑所有区域的结合[1]。
References	[1]. Schou M, et al. Discovery and Preclinical Validation of [(11)C]AZ13153556, a Novel Probe for the Histamine Type 3 Receptor. ACS Chem Neurosci. 2016 Feb 17;7(2):177-84. [2]. Nikolic K, et al. Procognitive properties of drugs with single and multitargeting H3 receptor antagonist activities. CNS Neurosci Ther. 2014 Jul;20(7):613-23.

Molecular Formula	C₁₉H₂₅N₃O₂
Molecular Weight	327.42

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