7-Deaza-ddG

Modify Date: 2024-01-09 01:10:58

7-Deaza-ddG structure	Common Name	7-Deaza-ddG
	CAS Number	111869-49-9	Molecular Weight	250.257
	Density	1.8±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₄N₄O₃	Melting Point	228 °C (decomp)
	MSDS	N/A	Flash Point	N/A

Use of 7-Deaza-ddG

7-Deaza-2',3'-dideoxyguanosine (7-Deaza-ddG) is a 2′,3′-dideoxynucleoside 5′-triphosphate, which can inhibit HIV-1 reverse transcriptase with a Ki of 25 nM[1].

Name	2-amino-7-(2,3-dideoxy-β-D-glycero-pentofuranosyl)-7H-pyrrolo<2,3-d>pyrimidin-4(3H)-one
Synonym	More Synonyms

Description	7-Deaza-2',3'-dideoxyguanosine (7-Deaza-ddG) is a 2′,3′-dideoxynucleoside 5′-triphosphate, which can inhibit HIV-1 reverse transcriptase with a Ki of 25 nM[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
Target	HIV-1
References	[1]. Nicholas A Boyle, et al. Synthesis of 2',3'-dideoxynucleoside 5'-alpha-P-borano-beta,gamma-(difluoromethylene)triphosphates and their inhibition of HIV-1 reverse transcriptase. J Med Chem. 2005 Apr 7;48(7):2695-700.

Density	1.8±0.1 g/cm3
Melting Point	228 °C (decomp)
Molecular Formula	C₁₁H₁₄N₄O₃
Molecular Weight	250.257
Exact Mass	250.106583
LogP	-1.43
Index of Refraction	1.797
Storage condition	2-8℃

MFCD07778654

4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-3,7-dihydro-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-

2-Amino-7-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furanyl]-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 7-Deaza-ddG
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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