icFSP1

Modify Date: 2024-01-23 21:19:39

icFSP1 Structure
icFSP1 structure
Common Name icFSP1
CAS Number 1115910-36-5 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of icFSP1


icFSP1 is a potent ferroptosis suppressor protein-1 (FSP1) inhibitor. icFSP1 does not competitively inhibit FSP1 enzyme activity, but instead triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation before ferroptosis induction, in synergism with GPX4 inhibition[1].

 Names

Name icFSP1

 icFSP1 Biological Activity

Description icFSP1 is a potent ferroptosis suppressor protein-1 (FSP1) inhibitor. icFSP1 does not competitively inhibit FSP1 enzyme activity, but instead triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation before ferroptosis induction, in synergism with GPX4 inhibition[1].
Related Catalog
References

[1]. Toshitaka Nakamura, et al. Phase separation of FSP1 promotes ferroptosis. Nature. 2023 Jul;619(7969):371-377.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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