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1115910-36-5

1115910-36-5 structure
1115910-36-5 structure
  • Name: icFSP1
  • Chemical Name: icFSP1
  • CAS Number: 1115910-36-5
  • Molecular Formula:
  • Molecular Weight:
  • Catalog: Signaling Pathways Apoptosis Ferroptosis
  • Create Date: 2023-10-20 13:54:55
  • Modify Date: 2024-01-23 21:19:39
  • icFSP1 is a potent ferroptosis suppressor protein-1 (FSP1) inhibitor. icFSP1 does not competitively inhibit FSP1 enzyme activity, but instead triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation before ferroptosis induction, in synergism with GPX4 inhibition[1].

Name icFSP1
Description icFSP1 is a potent ferroptosis suppressor protein-1 (FSP1) inhibitor. icFSP1 does not competitively inhibit FSP1 enzyme activity, but instead triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation before ferroptosis induction, in synergism with GPX4 inhibition[1].
Related Catalog
References

[1]. Toshitaka Nakamura, et al. Phase separation of FSP1 promotes ferroptosis. Nature. 2023 Jul;619(7969):371-377.  

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