Muramic acid

Modify Date: 2024-01-02 20:26:31

Muramic acid Structure
Muramic acid structure
Common Name Muramic acid
CAS Number 1114-41-6 Molecular Weight 251.23400
Density 1.51 g/cm3 Boiling Point 572.4ºC at 760 mmHg
Molecular Formula C9H17NO7 Melting Point 140-150 °C (dec.)
MSDS USA Flash Point 300ºC

 Use of Muramic acid


Muramic acid is a component in many Gram-positive bacterial cell walls, as marker for Gram-positive bacteria[1].

 Names

Name aldehydo-muramic acid
Synonym More Synonyms

 Muramic acid Biological Activity

Description Muramic acid is a component in many Gram-positive bacterial cell walls, as marker for Gram-positive bacteria[1].
Related Catalog
References

[1]. Lappalainen MHJ, et, al. High indoor microbial levels are associated with reduced Th1 cytokine secretion capacity in infancy. Int Arch Allergy Immunol. 2012; 159(2): 194-203.

 Chemical & Physical Properties

Density 1.51 g/cm3
Boiling Point 572.4ºC at 760 mmHg
Melting Point 140-150 °C (dec.)
Molecular Formula C9H17NO7
Molecular Weight 251.23400
Flash Point 300ºC
Exact Mass 251.10100
PSA 142.47000
Vapour Pressure 1.75E-15mmHg at 25°C
Index of Refraction 1.575
Storage condition −20°C

 MSDS

Name: Muramic Acid Hydrate Material Safety Data Sheet
Synonym: Non
CAS: 1114-41-6
Section 1 - Chemical Product MSDS Name:Muramic Acid Hydrate Material Safety Data Sheet
Synonym:Non

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
1114-41-6 Muramic Acid, Hydrate 100.0 214-214-9
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation. The toxicological properties of this material have not been fully investigated.
Skin:
May cause skin irritation. The toxicological properties of this material have not been fully investigated.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use only in a chemical fume hood.
Storage:
Store in a tightly closed container. Keep under an argon blanket.
Store in a cool, dry, well-ventilated area away from incompatible substances. Deep freeze (below -20C).

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 1114-41-6: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Decomposes
Freezing/Melting Point: 148 deg C dec
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: > 148 deg C
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C9H17NO7.xH2O
Molecular Weight: 251.24

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 1114-41-6 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Muramic Acid, Hydrate - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 1114-41-6: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 1114-41-6 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 1114-41-6 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 1

 Articles7

More Articles
Differential response of human nasal and bronchial epithelial cells upon exposure to size-fractionated dairy dust.

J. Toxicol. Environ. Health A 78 , 583-94, (2015)

Exposure to organic dusts is associated with increased respiratory morbidity and mortality in agricultural workers. Organic dusts in dairy farm environments are complex, polydisperse mixtures of toxic...

Synergistic Effects Between Thioxanthones and Oxacillin Against Methicillin-Resistant Staphylococcus aureus.

Microb. Drug Resist. 21 , 404-15, (2015)

The extensive use of antimicrobials is leaving medicine with few effective therapeutic options to treat many infections due to the fact that many organisms developed resistance to commonly used drugs....

The Staphylococcus aureus peptidoglycan protects mice against the pathogen and eradicates experimentally induced infection.

PLoS ONE 6 , e28377, (2011)

Staphylococcus aureus, in spite of antibiotics, is still a major human pathogen causing a wide range of infections. The present study describes the new vaccine A170PG, a peptidoglycan-based vaccine. I...

 Synonyms

EINECS 214-214-9
Muramic acid
2-Amino-3-O-(1-carboxyethyl)-2-deoxy-D-glucose
MFCD00213428
Top Suppliers:I want be here



Get all suppliers and price by the below link:

Muramic acid suppliers

Muramic acid price