4-Desmethoxy Omeprazole

Modify Date: 2024-01-21 12:48:27

4-Desmethoxy Omeprazole structure	Common Name	4-Desmethoxy Omeprazole
	CAS Number	110374-16-8	Molecular Weight	315.390
	Density	1.4±0.1 g/cm3	Boiling Point	584.7±60.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₇N₃O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	307.4±32.9 °C

Use of 4-Desmethoxy Omeprazole

4-Desmethoxy Omeprazole is the active metabolite of Omeprazole. Omeprazole, a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM[1]. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria[2].

Name	2-[(3,5-dimethylpyridin-2-yl)methylsulfinyl]-6-methoxy-1H-benzimidazole
Synonym	More Synonyms

Description	4-Desmethoxy Omeprazole is the active metabolite of Omeprazole. Omeprazole, a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM[1]. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria[2].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Research Areas >> Metabolic Disease
References	[1]. Li XQ, et al. Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities. Drug Metab Dispos. 2004 Aug;32(8):821-7. [2]. Jonkers D, et al. Omeprazole inhibits growth of gram-positive and gram-negative bacteria including Helicobacter pylori in vitro. J Antimicrob Chemother. 1996 Jan;37(1):145-50.

Description

Related Catalog

Research Areas >> Cancer

Research Areas >> Infection

Research Areas >> Metabolic Disease

References

[1]. Li XQ, et al. Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities. Drug Metab Dispos. 2004 Aug;32(8):821-7.

[2]. Jonkers D, et al. Omeprazole inhibits growth of gram-positive and gram-negative bacteria including Helicobacter pylori in vitro. J Antimicrob Chemother. 1996 Jan;37(1):145-50.

Density	1.4±0.1 g/cm3
Boiling Point	584.7±60.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₇N₃O₂S
Molecular Weight	315.390
Flash Point	307.4±32.9 °C
Exact Mass	315.104156
PSA	87.08000
LogP	1.90
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.687

Hazard Codes	Xi
HS Code	2933990090

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-[[(3,5-Dimethyl-2-pyridinyl)methyl]sulfinyl]-6-methoxy-1H-benzimidazole

2-(((3,5-Dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzo[d]imidazole

Omeprazole impurity B [EP]

4-Desmethoxy Omeprazole

UNII:0S4HQG5KFN

UNII-0S4HQG5KFN

1H-Benzimidazole, 2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-

2-{[(3,5-Dimethyl-2-pyridinyl)methyl]sulfinyl}-5-methoxy-1H-benzimidazole

Omeprazole magnesium impurity B [EP]

Esomeprazole Impurity 2

DC Chemicals Limited
China
Product Name: 4-Desmethoxy Omeprazole
Price:
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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