TMPDA

Modify Date: 2024-01-02 18:25:03

TMPDA Structure
TMPDA structure
Common Name TMPDA
CAS Number 110-95-2 Molecular Weight 130.231
Density 0.8±0.1 g/cm3 Boiling Point 143.3±8.0 °C at 760 mmHg
Molecular Formula C7H18N2 Melting Point N/A
MSDS USA Flash Point 31.7±0.0 °C
Symbol GHS02 GHS05 GHS06
GHS02, GHS05, GHS06
Signal Word Danger

 Names

Name N,N,N',N'-Tetramethyl-1,3-propanediamine
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.8±0.1 g/cm3
Boiling Point 143.3±8.0 °C at 760 mmHg
Molecular Formula C7H18N2
Molecular Weight 130.231
Flash Point 31.7±0.0 °C
Exact Mass 130.147003
PSA 6.48000
LogP 0.43
Vapour Pressure 5.4±0.3 mmHg at 25°C
Index of Refraction 1.442
Storage condition Flammables area
Stability Stable. Flammable. Incompatible with strong oxidizing agents, acids, acid chlorides, permanganates, carbon dioxide, nitrates, peroxides, nitrites, halogens.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TX8400000
CHEMICAL NAME :
1,3-Propanediamine, N,N,N',N'-tetramethyl-
CAS REGISTRY NUMBER :
110-95-2
BEILSTEIN REFERENCE NO. :
1734176
LAST UPDATED :
199801
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C7-H18-N2
MOLECULAR WEIGHT :
130.27
WISWESSER LINE NOTATION :
1N1&3N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
410 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
375 ppm/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
WADTAA Wright Air Development Center, Technical Report, U.S. Air Force. (Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: 55-250,10,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
300 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
>316 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 6,149,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
12 ppm/6H/30D-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - cough
REFERENCE :
WADTAA Wright Air Development Center, Technical Report, U.S. Air Force. (Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: 55-250,10,1955
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
12 ppm/6H/30D-I
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified
REFERENCE :
WADTAA Wright Air Development Center, Technical Report, U.S. Air Force. (Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: 55-250,10,1955

 Safety Information

Symbol GHS02 GHS05 GHS06
GHS02, GHS05, GHS06
Signal Word Danger
Hazard Statements H226-H302-H311-H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes T:Toxic;
Risk Phrases R10;R22;R24;R34
Safety Phrases S16-S26-S36/37/39-S45-S24/25
RIDADR UN 2734 8/PG 2
WGK Germany 2
RTECS TX8400000
Packaging Group III
Hazard Class 3
HS Code 2921290000

 Synthetic Route

 Customs

HS Code 2921290000
Summary 2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles4

More Articles
N,N,N',N'-Tetramethyl-1,3-propanediamine as the catalyst of choice for the Baylis-Hillman reaction of cycloalkenone: rate acceleration by stabilizing the zwitterionic intermediate via the ion-dipole interaction. Lee KY, et al.

Tetrahedron Lett. 45(28) , 5485-5488, (2004)

Synthesis of homodimeric monomethine cyanine dyes as noncovalent nucleic acid labels and their absorption and fluorescence spectral characteristics. Deligeorgiev TG, et al.

Dyes and Pigments 44(2) , 131-136, (2000)

Synthesis, physical properties, and structural characterization of. mu.-carbonato-dichlorobis (N,N,N',N'-Tetramethyl-1,3-propanediamine) dicopper(II), LCuCl(CO3)ClCuL, a diamagnetic initiator for the oxidative coupling of phenols by dioxygen. Churchill MR, et al.

Inorg. Chem. 18(8) , 2296-2300, (1979)

 Synonyms

bis[(dimethylamino)methyl]methane
N,N,N′,N′-Tetramethyl-1,3-propanediamine
N,N,N',N'-Tetramethylpropane-1,3-diamine
1,3-Propanediamine, N,N,N,N-tetramethyl-
N1,N1,N3,N3-Tetramethylpropane-1,3-diamine
Tetramethyl-1,3-diaminopropane
MFCD00008337
1,3-Bis(dimethylamino)propane
N,N,N',N'-Tetramethyltrimethylenediamine
N,N,N‘,N‘-Tetramethyl-1,3-propanediamine
TMPDA
N,N,N',N'-Tetramethyl-1,3-propanediamine
N,N,N',N'-TetraMethyl-1,3-diaMinopropane
EINECS 203-818-8
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