TMPDA
Names
[ CAS No. ]:
110-95-2
[ Name ]:
TMPDA
[Synonym ]:
bis[(dimethylamino)methyl]methane
N,N,N′,N′-Tetramethyl-1,3-propanediamine
N,N,N',N'-Tetramethylpropane-1,3-diamine
1,3-Propanediamine, N,N,N,N-tetramethyl-
N1,N1,N3,N3-Tetramethylpropane-1,3-diamine
Tetramethyl-1,3-diaminopropane
MFCD00008337
1,3-Bis(dimethylamino)propane
N,N,N',N'-Tetramethyltrimethylenediamine
N,N,N‘,N‘-Tetramethyl-1,3-propanediamine
TMPDA
N,N,N',N'-Tetramethyl-1,3-propanediamine
N,N,N',N'-TetraMethyl-1,3-diaMinopropane
EINECS 203-818-8
Chemical & Physical Properties
[ Density]:
0.8±0.1 g/cm3
[ Boiling Point ]:
143.3±8.0 °C at 760 mmHg
[ Molecular Formula ]:
C7H18N2
[ Molecular Weight ]:
130.231
[ Flash Point ]:
31.7±0.0 °C
[ Exact Mass ]:
130.147003
[ PSA ]:
6.48000
[ LogP ]:
0.43
[ Vapour Pressure ]:
5.4±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.442
[ Storage condition ]:
Flammables area
[ Stability ]:
Stable. Flammable. Incompatible with strong oxidizing agents, acids, acid chlorides, permanganates, carbon dioxide, nitrates, peroxides, nitrites, halogens.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TX8400000
- CHEMICAL NAME :
- 1,3-Propanediamine, N,N,N',N'-tetramethyl-
- CAS REGISTRY NUMBER :
- 110-95-2
- BEILSTEIN REFERENCE NO. :
- 1734176
- LAST UPDATED :
- 199801
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C7-H18-N2
- MOLECULAR WEIGHT :
- 130.27
- WISWESSER LINE NOTATION :
- 1N1&3N1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 410 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 375 ppm/2H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- WADTAA Wright Air Development Center, Technical Report, U.S. Air Force. (Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: 55-250,10,1955
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 300 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - quail
- DOSE/DURATION :
- >316 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 6,149,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 12 ppm/6H/30D-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - cough
- REFERENCE :
- WADTAA Wright Air Development Center, Technical Report, U.S. Air Force. (Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: 55-250,10,1955
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 12 ppm/6H/30D-I
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified
- REFERENCE :
- WADTAA Wright Air Development Center, Technical Report, U.S. Air Force. (Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: 55-250,10,1955
Safety Information
[ Symbol ]:
GHS02, GHS05, GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H226-H302-H311-H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R10;R22;R24;R34
[ Safety Phrases ]:
S16-S26-S36/37/39-S45-S24/25
[ RIDADR ]:
UN 2734 8/PG 2
[ WGK Germany ]:
2
[ RTECS ]:
TX8400000
[ Packaging Group ]:
III
[ Hazard Class ]:
3
[ HS Code ]:
2921290000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921290000
[ Summary ]:
2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
Tetrahedron Lett. 45(28) , 5485-5488, (2004)
Synthesis of homodimeric monomethine cyanine dyes as noncovalent nucleic acid labels and their absorption and fluorescence spectral characteristics. Deligeorgiev TG, et al.
Dyes and Pigments 44(2) , 131-136, (2000)
Synthesis, physical properties, and structural characterization of. mu.-carbonato-dichlorobis (N,N,N',N'-Tetramethyl-1,3-propanediamine) dicopper(II), LCuCl(CO3)ClCuL, a diamagnetic initiator for the oxidative coupling of phenols by dioxygen. Churchill MR, et al.
Inorg. Chem. 18(8) , 2296-2300, (1979)