PC-766B

Modify Date: 2024-01-10 18:30:14

PC-766B structure	Common Name	PC-766B
	CAS Number	108375-77-5	Molecular Weight	776.99
	Density	1.17g/cm3	Boiling Point	884.3ºC at 760mmHg
	Molecular Formula	C₄₃H₆₈O₁₂	Melting Point	N/A
	MSDS	N/A	Flash Point	255.2ºC

Use of PC-766B

PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na+, K+-ATPase[1][2].

Name	(3E,5Z,7R,8S,9S,11Z,13Z,15S,16R)-16-[(3R,4S)-4-[(2R,4R,5S,6R)-4-[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-2-hydroxy-5-methyl-6-[(1E,3E)-penta-1,3-dienyl]oxan-2-yl]-3-hydroxypentan-2-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexa
Synonym	More Synonyms

Description	PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na+, K+-ATPase[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Kumagai K, et, al. PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. I. Taxonomy, fermentation and biological activity. J Antibiot (Tokyo). 1993 Jun;46(6):972-8. [2]. Kumagai K, et, al. PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. II. Isolation, physico-chemical properties and structure elucidation. J Antibiot (Tokyo). 1993 Jul;46(7):1139-44.

Description

Related Catalog

Research Areas >> Cancer

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

Signaling Pathways >> Anti-infection >> Bacterial

References

[1]. Kumagai K, et, al. PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. I. Taxonomy, fermentation and biological activity. J Antibiot (Tokyo). 1993 Jun;46(6):972-8.

[2]. Kumagai K, et, al. PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. II. Isolation, physico-chemical properties and structure elucidation. J Antibiot (Tokyo). 1993 Jul;46(7):1139-44.

Density	1.17g/cm3
Boiling Point	884.3ºC at 760mmHg
Molecular Formula	C₄₃H₆₈O₁₂
Molecular Weight	776.99
Flash Point	255.2ºC
Exact Mass	776.47100
PSA	173.60000
LogP	5.05000
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.555

pc 766b

PC-766B

Use of PC-766B

Names

PC-766B Biological Activity

Chemical & Physical Properties

Synonyms