PC-766B

Modify Date: 2025-08-22 12:50:40

PC-766B Structure
PC-766B structure
Common Name PC-766B
CAS Number 108375-77-5 Molecular Weight 776.99
Density 1.17g/cm3 Boiling Point 884.3ºC at 760mmHg
Molecular Formula C43H68O12 Melting Point N/A
MSDS N/A Flash Point 255.2ºC

 Use of PC-766B


PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na+, K+-ATPase[1][2].

 Names

Name (3E,5Z,7R,8S,9S,11Z,13Z,15S,16R)-16-[(3R,4S)-4-[(2R,4R,5S,6R)-4-[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-2-hydroxy-5-methyl-6-[(1E,3E)-penta-1,3-dienyl]oxan-2-yl]-3-hydroxypentan-2-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexa
Synonym More Synonyms

 PC-766B Biological Activity

Description PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na+, K+-ATPase[1][2].
Related Catalog
References

[1]. Kumagai K, et, al. PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. I. Taxonomy, fermentation and biological activity. J Antibiot (Tokyo). 1993 Jun;46(6):972-8.  

[2]. Kumagai K, et, al. PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. II. Isolation, physico-chemical properties and structure elucidation. J Antibiot (Tokyo). 1993 Jul;46(7):1139-44.  

 Chemical & Physical Properties

Density 1.17g/cm3
Boiling Point 884.3ºC at 760mmHg
Molecular Formula C43H68O12
Molecular Weight 776.99
Flash Point 255.2ºC
Exact Mass 776.47100
PSA 173.60000
LogP 5.05000
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.555
InChIKey GBRLJEHLCUILHG-KIRYWGJYSA-N
SMILES CC=CC=CC1OC(O)(C(C)C(O)C(C)C2OC(=O)C(OC)=CC(C)=CC(C)C(O)C(C)CC(C)=CC=CC2OC)CC(OC2CC(O)C(O)C(C)O2)C1C

 Synonyms

pc 766b
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