ST638
ST638 structure
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Common Name | ST638 | ||
|---|---|---|---|---|
| CAS Number | 107761-24-0 | Molecular Weight | 354.423 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 611.2±55.0 °C at 760 mmHg | |
| Molecular Formula | C19H18N2O3S | Melting Point | 134-135.5ºC | |
| MSDS | Chinese USA | Flash Point | 323.5±31.5 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of ST638ST638 is a potent tyrosine kinase inhibitor with an IC50 of 370 nM[1]. |
| Name | 2-cyano-3-[3-ethoxy-4-hydroxy-5-(phenylsulfanylmethyl)phenyl]prop-2-enamide |
|---|---|
| Synonym | More Synonyms |
| Description | ST638 is a potent tyrosine kinase inhibitor with an IC50 of 370 nM[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 611.2±55.0 °C at 760 mmHg |
| Melting Point | 134-135.5ºC |
| Molecular Formula | C19H18N2O3S |
| Molecular Weight | 354.423 |
| Flash Point | 323.5±31.5 °C |
| Exact Mass | 354.103821 |
| PSA | 121.64000 |
| LogP | 2.34 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.656 |
| InChIKey | YKLMGKWXBLSKPK-RIYZIHGNSA-N |
| SMILES | CCOc1cc(C=C(C#N)C(N)=O)cc(CSc2ccccc2)c1O |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| HS Code | 2930909090 |
|---|---|
| Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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The effect of a naphthalene derivative, TEI-6472, on histamine release and tyrosine phosphorylation in rat basophilic leukemia cells.
Int. J. Immunopharmacol. 17(5) , 433-41, (1995) It is well known that rat basophilic leukemia cells (RBL-2H3) express high-affinity IgE receptors (Fc epsilon RI) and that the aggregation of these receptors causes the release of chemical mediators. ... |
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Inhibition of fast sodium current in rabbit ventricular myocytes by protein tyrosine kinase inhibitors.
Pflugers Arch. 446(4) , 485-91, (2003) The present study investigated the effects of protein tyrosine kinase inhibitors on the fast sodium current ( I(Na)) in rabbit ventricular myocytes. Single rabbit ventricular myocytes were isolated en... |
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Involvement of phosphatidic acid in both degranulation and oxidative activity in fMet-Leu-Phe stimulated polymorphonuclear leukocytes.
Cell Physiol. Biochem. 13(3) , 165-72, (2003) Polymorphonuclear leukocytes (neutrophils) release a variety of toxic agents--proteins and reactive oxygen species (ROS)--that are used to inactivate foreign microorganisms in the non-specific immune ... |
| 2-Propenamide, 2-cyano-3-[3-ethoxy-4-hydroxy-5-[(phenylthio)methyl]phenyl]-, (2E)- |
| MFCD00236446 |
| (2E)-2-Cyano-3-{3-ethoxy-4-hydroxy-5-[(phenylsulfanyl)methyl]phenyl}acrylamide |
| ST638 (pharmaceutical) |
| 2-Propenamide,2-cyano-3-[3-ethoxy-4-hydroxy-5-[(phenylthio)methyl]phenyl] |
| ST 638 |