Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ST638
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Purity: 98.0%
Stocking Period: 10 Day
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DC Chemicals Limited
China
Product Name: ST638
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

107761-24-0

107761-24-0 structure

107761-24-0 structure

Name: ST638
Chemical Name: 2-cyano-3-[3-ethoxy-4-hydroxy-5-(phenylsulfanylmethyl)phenyl]prop-2-enamide
CAS Number: 107761-24-0
Molecular Formula: C₁₉H₁₈N₂O₃S
Molecular Weight: 354.423
Create Date: 2018-12-28 23:33:03
Modify Date: 2025-08-20 19:19:59
ST638 is a potent tyrosine kinase inhibitor with an IC50 of 370 nM[1].

Name	2-cyano-3-[3-ethoxy-4-hydroxy-5-(phenylsulfanylmethyl)phenyl]prop-2-enamide
Synonyms	2-Propenamide, 2-cyano-3-[3-ethoxy-4-hydroxy-5-[(phenylthio)methyl]phenyl]-, (2E)- MFCD00236446 (2E)-2-Cyano-3-{3-ethoxy-4-hydroxy-5-[(phenylsulfanyl)methyl]phenyl}acrylamide ST638 (pharmaceutical) 2-Propenamide,2-cyano-3-[3-ethoxy-4-hydroxy-5-[(phenylthio)methyl]phenyl] ST 638

Description	ST638 is a potent tyrosine kinase inhibitor with an IC50 of 370 nM[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Fuortes M, et al. Adhesion-dependent protein tyrosine phosphorylation in neutrophils treated with tumor necrosis factor. J Cell Biol. 1993 Feb;120(3):777-84.

Density	1.3±0.1 g/cm3
Boiling Point	611.2±55.0 °C at 760 mmHg
Melting Point	134-135.5ºC
Molecular Formula	C₁₉H₁₈N₂O₃S
Molecular Weight	354.423
Flash Point	323.5±31.5 °C
Exact Mass	354.103821
PSA	121.64000
LogP	2.34
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.656

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UC6316200

CHEMICAL NAME :: 2-Propenamide, 2-cyano-3-(3-ethoxy-4-hydroxy-5-((phenylthio)methyl)p henyl)-

CAS REGISTRY NUMBER :: 107761-24-0

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C19-H18-N2-O3-S

MOLECULAR WEIGHT :: 354.45

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #93-00938

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #93-00938

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	UC6316200
HS Code	2930909090

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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