Cochliodone A
Modify Date: 2024-01-17 14:42:37
Cochliodone A structure
|
Common Name | Cochliodone A | ||
|---|---|---|---|---|
| CAS Number | 1072931-48-6 | Molecular Weight | 638.66 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 774.1±60.0 °C at 760 mmHg | |
| Molecular Formula | C34H38O12 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 421.9±32.9 °C | |
Use of Cochliodone ACochliodone A is an active compound extracted from cultures of the deep-sea derived fungus Chaetomium sp. and has antibacterial and anticancer activity. Cochliodone A is toxic to a variety of bacteria, with MICs of 15.3 μg/mL (V. vulnificus), 32.7 μg/mL (V. rotiferianus), 15.9 μg/mL (S. aureus ATCC 43300), and 16.3 μg/mL (S . aureus CGMCC 1.12409). Cochliodone A also inhibits a variety of cancer cell lines, with IC50s of 28.1 μM (A549), 20.7 μM (HeLa), and 23.2 μM (Hep G2)[1]. |
| Name | (1Z,4S,5Z,11aR,14S,14aR,15S,15aR,16aS,16bR)-14-(1H-Indol-3-ylmethyl)-4,6,15,15a-tetramethyl-9,10,14,14a,15,15a,16a,16b-octahydro-3H-cyclotrideca[d]oxireno[f]isoindole-7,8,11,12(4H,13H)-tetrone |
|---|---|
| Synonym | More Synonyms |
| Description | Cochliodone A is an active compound extracted from cultures of the deep-sea derived fungus Chaetomium sp. and has antibacterial and anticancer activity. Cochliodone A is toxic to a variety of bacteria, with MICs of 15.3 μg/mL (V. vulnificus), 32.7 μg/mL (V. rotiferianus), 15.9 μg/mL (S. aureus ATCC 43300), and 16.3 μg/mL (S . aureus CGMCC 1.12409). Cochliodone A also inhibits a variety of cancer cell lines, with IC50s of 28.1 μM (A549), 20.7 μM (HeLa), and 23.2 μM (Hep G2)[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 774.1±60.0 °C at 760 mmHg |
| Molecular Formula | C34H38O12 |
| Molecular Weight | 638.66 |
| Flash Point | 421.9±32.9 °C |
| Exact Mass | 528.262451 |
| LogP | 3.45 |
| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
| Index of Refraction | 1.633 |
| 3H-Cyclotridec[d]oxireno[f]isoindole-7,8,11,12(4H,13H)-tetrone, 9,10,14,14a,15,15a,16a,16b-octahydro-14-(1H-indol-3-ylmethyl)-4,6,15,15a-tetramethyl-, (1Z,4S,5Z,11aR,14S,14aR,15S,15aR,16aS,16bR)- |
| (1Z,4S,5Z,11aR,14S,14aR,15S,15aR,16aS,16bR)-14-(1H-Indol-3-ylmethyl)-4,6,15,15a-tetramethyl-9,10,14,14a,15,15a,16a,16b-octahydro-3H-cyclotrideca[d]oxireno[f]isoindole-7,8,11,12(4H,13H)-tetrone |