Quercetin pentaacetate

Modify Date: 2024-01-11 17:18:55

Quercetin pentaacetate Structure
Quercetin pentaacetate structure
Common Name Quercetin pentaacetate
CAS Number 1064-06-8 Molecular Weight 512.41900
Density 1.45g/cm3 Boiling Point 666.4ºC at 760 mmHg
Molecular Formula C25H20O12 Melting Point N/A
MSDS N/A Flash Point 284.7ºC

 Use of Quercetin pentaacetate


Quercetin pentaacetate could interact with F-protein with lower binding energy and better stability to block viral adhesion. Quercetin pentaacetate interacts with RSV and inhibit the viral adhesion on cell surface[1][2].

 Names

Name [2-acetyloxy-4-(3,5,7-triacetyloxy-4-oxochromen-2-yl)phenyl] acetate
Synonym More Synonyms

 Quercetin pentaacetate Biological Activity

Description Quercetin pentaacetate could interact with F-protein with lower binding energy and better stability to block viral adhesion. Quercetin pentaacetate interacts with RSV and inhibit the viral adhesion on cell surface[1][2].
Related Catalog
In Vitro Quercetin pentaacetate (0-40 μM) shows the obvious inhibition on LPS-induced PGE2 production and COX-2 gene expression and the inhibition in NLA/LPS or L-NAME/LPS co-treated RAW 264.7 cells[2].
References

[1]. Bruno Rafael Pereira Lopes, et al. Quercetin Pentaacetate Inhibits in Vitro Human Respiratory Syncytial Virus Adhesion. Virus Res. 2020 Jan 15;276:197805.

[2]. Y C Chen, et al. Inhibition of Nitric Oxide Synthase Inhibitors and Lipopolysaccharide Induced Inducible NOS and cyclooxygenase-2 Gene Expressions by Rutin, Quercetin, and Quercetin Pentaacetate in RAW 264.7 Macrophages. J Cell Biochem. 2001;82(4):537-48.

 Chemical & Physical Properties

Density 1.45g/cm3
Boiling Point 666.4ºC at 760 mmHg
Molecular Formula C25H20O12
Molecular Weight 512.41900
Flash Point 284.7ºC
Exact Mass 512.09500
PSA 161.71000
LogP 3.08650
Vapour Pressure 1.27E-17mmHg at 25°C
Index of Refraction 1.6

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LK8985000
CHEMICAL NAME :
Flavone, 3,3',4',5,7-pentahydroxy-, pentaacetate
CAS REGISTRY NUMBER :
1064-06-8
BEILSTEIN REFERENCE NO. :
0380215
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C25-H20-O12
MOLECULAR WEIGHT :
512.45
WISWESSER LINE NOTATION :
T66 BO EVJ CR COV1 DOV1& DOV1 GOV1 IOV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
5 ug/plate
REFERENCE :
SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 197,577,1977

 Safety Information

HS Code 2915900090

 Customs

HS Code 2915900090
Summary 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

 Synonyms

Quercetin acetate
penta-O-acetylquercetin
Pentaacetylquercetin
quercetin pentaacetate
3,3',4',5,7-Pentahydroxyflavone pentaacetate
3,3',4',5,7-Pentaacetoxyflavone
FLAVONE,3,3',4',5,7-PENTAHYDROXY-,PENTAACETATE
quercetin peracetate