Mometasone

Modify Date: 2025-08-26 00:03:06

Mometasone Structure
Mometasone structure
Common Name Mometasone
CAS Number 105102-22-5 Molecular Weight 521.42900
Density 1.35g/cm3 Boiling Point 586.6ºC at 760mmHg
Molecular Formula C27H30Cl2O6 Melting Point 220ºC (decomposes)
MSDS N/A Flash Point 308.5ºC

 Use of Mometasone


Mometasone is an inhaled glucocorticoid. Mometasone can be used in mild asthma with a low sputum eosinophil level. Mometasone has the potential for the research of chronic hand eczema and rhinosinusitis[1][2].

 Names

Name mometasone
Synonym More Synonyms

 Mometasone Biological Activity

Description Mometasone is an inhaled glucocorticoid. Mometasone can be used in mild asthma with a low sputum eosinophil level. Mometasone has the potential for the research of chronic hand eczema and rhinosinusitis[1][2].
Related Catalog
In Vivo Mometasone (0.1-3 mg/kg; intranasally) inhibits the increased airway sensitivity to aerosolized methacholine at the highest dose tested of 3 mg/kg, and dose-dependently inhibits the allergen-induced increase in Penh in a mouse model of allergic lung inflammation[3].
References

[1]. Veien NK, et al. Long-term, intermittent treatment of chronic hand eczema with mometasone furoate. Br J Dermatol. 1999 May;140(5):882-6.

[2]. Lazarus SC, et al. Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level. N Engl J Med. 2019 May 23;380(21):2009-2019.

[3]. Wyss D, et al. Synergistic effect of formoterol and mometasone in a mouse model of allergic lung inflammation. Br J Pharmacol. 2007 Sep;152(1):83-90.

 Chemical & Physical Properties

Density 1.35g/cm3
Boiling Point 586.6ºC at 760mmHg
Melting Point 220ºC (decomposes)
Molecular Formula C27H30Cl2O6
Molecular Weight 521.42900
Flash Point 308.5ºC
Exact Mass 520.14200
PSA 93.81000
LogP 4.86920
Vapour Pressure 4.47E-18mmHg at 25°C
Index of Refraction 1.603

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

9a,21-dichloro-11b,17-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione
MFCD02683426
Pregna-1,4-diene-3,20-dione,9,21-dichloro-11,17-dihydroxy-16-methyl-,(11b,16a)-(9CI)
Mometasone
MOMETOSONE FUROATE
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