Dihydroethidium

Modify Date: 2025-08-24 19:26:10

Dihydroethidium Structure
Dihydroethidium structure
 Common Name Dihydroethidium
CAS Number 104821-25-2 Molecular Weight 315.411
Density 1.2±0.1 g/cm3 Boiling Point 580.4±50.0 °C at 760 mmHg
Molecular Formula C21H21N3 Melting Point N/A
MSDS Chinese USA Flash Point 299.5±24.9 °C

 Use of Dihydroethidium


Dihydroethidium(Hydroethidine; PD-MY 003) is a superoxide indicator; exhibits blue-fluorescence in the cytosol until oxidized, where it intercalates within the cell's DNA, staining its nucleus a bright fluorescent red.

 Names

Name Dihydroethidium
Synonym More Synonyms

 Dihydroethidium Biological Activity

Description Dihydroethidium(Hydroethidine; PD-MY 003) is a superoxide indicator; exhibits blue-fluorescence in the cytosol until oxidized, where it intercalates within the cell's DNA, staining its nucleus a bright fluorescent red.
Related Catalog
References

[1]. Zielonka J, et al. Global profiling of reactive oxygen and nitrogen species in biological systems: high-throughput real-time analyses. J Biol Chem. 2012 Jan 27;287(5):2984-95.

[2]. Kwong C, et al. Tumor-associated a2 vacuolar ATPase acts as a key mediator of cancer-related inflammation by inducing pro-tumorigenic properties in monocytes. J Immunol. 2011 Feb 1;186(3):1781-9.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 580.4±50.0 °C at 760 mmHg
Molecular Formula C21H21N3
Molecular Weight 315.411
Flash Point 299.5±24.9 °C
Exact Mass 315.173553
PSA 55.92000
LogP 3.06
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.680
InChIKey XYJODUBPWNZLML-UHFFFAOYSA-N
SMILES CCN1c2cc(N)ccc2-c2ccc(N)cc2C1c1ccccc1
Storage condition −20°C
Water Solubility acetonitrile: soluble

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933990090

 Synthetic Route

Ethidium bromide structure

Ethidium bromide

CAS#:1239-45-8

~%

Dihydroethidium Structure

Dihydroethidium

CAS#:104821-25-2

Literature: Tetrahedron, , vol. 45, # 11 p. 3385 - 3396

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

3,8-Phenanthridinediamine, 5-ethyl-5,6-dihydro-6-phenyl-
3,8-Phenanthridinediamine, 5-ethyl-5,6-dihydro-6-phenyl-, (±)-
dihydroethidium
MFCD00077335
5,6-dihydro-3,8-diamino-5-ethyl-6-phenylphenanthridine
5-Ethyl-6-phenyl-5,6-dihydro-3,8-phenanthridinediamine
Phenanthridine, 5,6-dihydro-3,8-diamino-5-ethyl-6-phenyl-
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