Apricolin

Modify Date: 2024-01-02 18:47:45

Apricolin Structure
Apricolin structure
Common Name Apricolin
CAS Number 104-61-0 Molecular Weight 156.222
Density 1.0±0.1 g/cm3 Boiling Point 266.6±0.0 °C at 760 mmHg
Molecular Formula C9H16O2 Melting Point N/A
MSDS Chinese USA Flash Point 98.8±15.9 °C

 Names

Name gamma-Nonanolactone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 266.6±0.0 °C at 760 mmHg
Molecular Formula C9H16O2
Molecular Weight 156.222
Flash Point 98.8±15.9 °C
Exact Mass 156.115036
PSA 26.30000
LogP 1.85
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.444

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LU3675000
CHEMICAL NAME :
2(3H)-Furanone, dihydro-5-pentyl-
CAS REGISTRY NUMBER :
104-61-0
LAST UPDATED :
199712
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C9-H16-O2
MOLECULAR WEIGHT :
156.25
WISWESSER LINE NOTATION :
T5OVTJ E5

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
3440 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Gastrointestinal - changes in structure or function of salivary glands

MUTATION DATA

TYPE OF TEST :
DNA repair
TEST SYSTEM :
Bacteria - Bacillus subtilis
DOSE/DURATION :
20 mg/disc
REFERENCE :
OIGZDE Osaka-shi Igakkai Zasshi. Journal of Osaka City Medical Association. (Osaka-shi Igakkai, c/o Osaka-shiritsu Daigaku Igakubu, 1-4-54 Asahi-cho, Abeno-ku, Osaka, 545, Japan) V.24- 1975- Volume(issue)/page/year: 34,267,1985 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83196 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 19 No. of Employees: 2695 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83196 No. of Facilities: 1381 (estimated) No. of Industries: 6 No. of Occupations: 8 No. of Employees: 11047 (estimated) No. of Female Employees: 4717 (estimated)

 Safety Information

Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi
Safety Phrases S24/25-S22
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS LU3675000
HS Code 2932209090

 Synthetic Route

 Customs

HS Code 2932209090
Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles4

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J. Med. Chem. 48 , 3808-15, (2005)

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The catalytic histidine dyad of high density lipoprotein-associated serum paraoxonase-1 (PON1) is essential for PON1-mediated inhibition of low density lipoprotein oxidation and stimulation of macrophage cholesterol efflux.

J. Biol. Chem. 281(11) , 7657-65, (2006)

High density lipoprotein (HDL)-associated paraoxonase-1 (PON1) anti-atherogenic properties in macrophages, i.e. inhibition of cell-mediated oxidation of low density lipoprotein (LDL) and stimulation o...

Determination of volatile oak compounds in wine by headspace solid-phase microextraction and gas chromatography-mass spectrometry.

J. Chromatogr. A. 1102(1-2) , 25-36, (2006)

A headspace solid-phase microextraction (HS-SPME) and gas chromatography (GC) coupled to mass spectrometry (MS) method was developed to identify and quantify 14 volatile oak compounds in aged red wine...

 Synonyms

Dihydro-5-pentyl-2(3H)-furanon
Apricolin
g-Nonanolide
UNII:I1XGH66S8P
5-Pentyldihydro-2(3H)-furanone
d-n-Amylbutyrolactone
γ-Nonalactone
2(3H)-Furanone, dihydro-5-pentyl-
g-Pentyl-g-butyrolactone
5-pentyldihydrofuran-2(3H)-one
Gamma-Nonanolactone
γ-Pelargonolactone
MFCD00005403
γ-Nonanolactone
EINECS 203-219-1
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