9H-Purine-2,6-diamine, 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-

Modify Date: 2024-01-29 19:48:50

9H-Purine-2,6-diamine, 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)- Structure
9H-Purine-2,6-diamine, 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)- structure
Common Name 9H-Purine-2,6-diamine, 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-
CAS Number 103884-97-5 Molecular Weight 284.25
Density N/A Boiling Point N/A
Molecular Formula C10H13FN6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 9H-Purine-2,6-diamine, 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-


2,6-Diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

 Names

Name 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine-2,6-diamine
Synonym More Synonyms

  Biological Activity

Description 2,6-Diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog
References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

 Chemical & Physical Properties

Molecular Formula C10H13FN6O3
Molecular Weight 284.25
Exact Mass 284.10300
PSA 145.33000

 Synonyms

2,6-diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)purine
2-amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine
2,6-Diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine
2,6-diamino-9-(2-fluoro-β-D-arabinosyl)purine