Halichondrin B
Modify Date: 2025-08-25 11:10:29
Halichondrin B structure
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Common Name | Halichondrin B | ||
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| CAS Number | 103614-76-2 | Molecular Weight | 1111.31000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C60H86O19 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Halichondrin BHalichondrin B is found from the sponge Halichondria okadai. Halichondrin B is a noncompetitive inhibitor of Vinca-alkaloid binding to tubulin (IC50 for tubulin polymerization of 1.2-1.4 μM). Halichondrin B shows anti-tumor activity[1]. |
| Name | Halichondrin B |
|---|---|
| Synonym | More Synonyms |
| Description | Halichondrin B is found from the sponge Halichondria okadai. Halichondrin B is a noncompetitive inhibitor of Vinca-alkaloid binding to tubulin (IC50 for tubulin polymerization of 1.2-1.4 μM). Halichondrin B shows anti-tumor activity[1]. |
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| Related Catalog | |
| In Vitro | Halichondrin B (0.1-10 nM, 16 h) treatment inhibits the growth of L1210 cells[1]. Cell Cytotoxicity Assay[1] Cell Line: L1210 cells Concentration: 0.1-10 nM Incubation Time: 16 hours Result: Inhibited L1210 cell with IC50 value of 0.3 nM. |
| References |
| Molecular Formula | C60H86O19 |
|---|---|
| Molecular Weight | 1111.31000 |
| Exact Mass | 1110.58000 |
| PSA | 216.21000 |
| LogP | 4.92540 |
| halichondrin B |