LCS-1.28

Modify Date: 2023-01-14 16:55:46

LCS-1.28 structure	Common Name	LCS-1.28
	CAS Number	1035450-90-8	Molecular Weight	344.002
	Density	1.8±0.1 g/cm3	Boiling Point	371.2±52.0 °C at 760 mmHg
	Molecular Formula	C₁₁H₈Br₂N₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	178.3±30.7 °C

Use of LCS-1.28

LCS-1.28 is a small molecule that inhibits growth of human lung adenocarcinoma cells harboring mutations in EGFR or KRAS with IC50 of 0.05-1.6 uM; superoxide dismutase 1 (SOD1) are the most likely target of LCS-1, LCS-1.28 inhibits SOD1 in a dose-dependent manner with IC50 of 0.95 uM.

Name	4,5-Dibromo-2-(3-methylphenyl)-3(2H)-pyridazinone
Synonym	More Synonyms

Description	LCS-1.28 is a small molecule that inhibits growth of human lung adenocarcinoma cells harboring mutations in EGFR or KRAS with IC50 of 0.05-1.6 uM; superoxide dismutase 1 (SOD1) are the most likely target of LCS-1, LCS-1.28 inhibits SOD1 in a dose-dependent manner with IC50 of 0.95 uM.
References	References 1. Somwar R, et al. J Biomol Screen. 2009 Dec;14(10):1176-84. 2. Somwar R, et al. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16375-80. View Related Products by Target Other Targets

Density	1.8±0.1 g/cm3
Boiling Point	371.2±52.0 °C at 760 mmHg
Molecular Formula	C₁₁H₈Br₂N₂O
Molecular Weight	344.002
Flash Point	178.3±30.7 °C
Exact Mass	341.900330
LogP	2.56
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.671

4,5-Dibromo-2-(3-methylphenyl)-3(2H)-pyridazinone

3(2H)-Pyridazinone, 4,5-dibromo-2-(3-methylphenyl)-

MFCD12079180

DC Chemicals Limited
China
Product Name: LCS-1.28
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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