24725-65-3
24725-65-3 structure
- Name: LCS-1.34
- Chemical Name: 4,5-dichloro-2-(2,4-dichlorophenyl)pyridazin-3-one
- CAS Number: 24725-65-3
- Molecular Formula: C10H4Cl4N2O
- Molecular Weight: 309.96400
- Create Date: 2018-12-24 13:48:11
- Modify Date: 2025-09-10 01:06:48
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LCS-1.34 is a small molecule that inhibits growth of human lung adenocarcinoma cells harboring mutations in EGFR or KRAS with IC50 of 0.1-1.1 uM.
| Name | 4,5-dichloro-2-(2,4-dichlorophenyl)pyridazin-3-one |
|---|---|
| Synonyms |
4,5-dichloro-2-(2,4-dichloro-phenyl)-2H-pyridazin-3-one
4,5-Dichlor-1-(2,4-dichlor-phenyl)-pyridaz-6-on 4,5-dichloro-2-(2,4-dichlorophenyl)-2,3-dihydropyridazin-3-one |
| Density | 1.66g/cm3 |
|---|---|
| Boiling Point | 378.5ºC at 760mmHg |
| Molecular Formula | C10H4Cl4N2O |
| Molecular Weight | 309.96400 |
| Exact Mass | 307.90800 |
| PSA | 34.89000 |
| LogP | 3.84610 |
| Vapour Pressure | 6.27E-06mmHg at 25°C |
| Index of Refraction | 1.67 |
| Risk Phrases | 36/37/38 |
|---|---|
| Safety Phrases | 26-36/37/39 |
| HS Code | 2933990090 |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |