CRT5
Modify Date: 2025-08-26 20:02:52
CRT5 structure
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Common Name | CRT5 | ||
|---|---|---|---|---|
| CAS Number | 1034297-58-9 | Molecular Weight | 454.563 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 651.2±55.0 °C at 760 mmHg | |
| Molecular Formula | C28H30N4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 347.6±31.5 °C | |
Use of CRT5CRT5, a pyrazine benzamide, is a potent and selective inhibitor for all three isoforms of PKD in endothelial cells treated with VEGF (IC50s = 1, 2, and 1.5 nM for PKD1, PKD2, and PKD3, respectively). CRT5 decreases VEGF-induced endothelial migration, proliferation and tubulogenesis[1]. |
| Name | 3-[6-Amino-5-(6-ethoxy-2-naphthyl)-3-pyridinyl]-N-[2-(dimethylamino)ethyl]benzamide |
|---|---|
| Synonym | More Synonyms |
| Description | CRT5, a pyrazine benzamide, is a potent and selective inhibitor for all three isoforms of PKD in endothelial cells treated with VEGF (IC50s = 1, 2, and 1.5 nM for PKD1, PKD2, and PKD3, respectively). CRT5 decreases VEGF-induced endothelial migration, proliferation and tubulogenesis[1]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 651.2±55.0 °C at 760 mmHg |
| Molecular Formula | C28H30N4O2 |
| Molecular Weight | 454.563 |
| Flash Point | 347.6±31.5 °C |
| Exact Mass | 454.236877 |
| LogP | 5.22 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.632 |
| InChIKey | XBDRAUPLGHAFCU-UHFFFAOYSA-N |
| SMILES | CCOc1ccc2cc(-c3cc(-c4cccc(C(=O)NCCN(C)C)c4)cnc3N)ccc2c1 |
| Benzamide, 3-[6-amino-5-(6-ethoxy-2-naphthalenyl)-3-pyridinyl]-N-[2-(dimethylamino)ethyl]- |
| MFCD29081160 |
| 3-[6-Amino-5-(6-ethoxy-2-naphthyl)-3-pyridinyl]-N-[2-(dimethylamino)ethyl]benzamide |
| CRT5 |