2'-O-Methyl-5'-O-DMT-Uridine;DMT-2'-OMe-U

Modify Date: 2024-01-09 06:58:52

2'-O-Methyl-5'-O-DMT-Uridine;DMT-2'-OMe-U Structure
2'-O-Methyl-5'-O-DMT-Uridine;DMT-2'-OMe-U structure
Common Name 2'-O-Methyl-5'-O-DMT-Uridine;DMT-2'-OMe-U
CAS Number 103285-22-9 Molecular Weight 560.59
Density N/A Boiling Point N/A
Molecular Formula C31H32N2O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2'-O-Methyl-5'-O-DMT-Uridine;DMT-2'-OMe-U


5’-O-(4,4’-Dimethoxytrityl)-2’-O-methyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].

 Names

Name 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione
Synonym More Synonyms

  Biological Activity

Description 5’-O-(4,4’-Dimethoxytrityl)-2’-O-methyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].
Related Catalog
References

[1]. Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.  

 Chemical & Physical Properties

Molecular Formula C31H32N2O8
Molecular Weight 560.59
Exact Mass 560.21600
PSA 121.24000
LogP 2.83580
Appearance of Characters Powder | White to Pale Yellow
Storage condition Store dry at 2-8°C

 Synthetic Route

~65%

2'-O-Methyl-5'-O-DMT-Uridine;DMT-2'-OMe-U Structure

2'-O-Methyl-5'-...

CAS#:103285-22-9

Literature: Buettner, Lea; Seikowski, Jan; Wawrzyniak, Katarzyna; Ochmann, Anne; Hoebartner, Claudia Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 20 p. 6171 - 6180

~99%

2'-O-Methyl-5'-O-DMT-Uridine;DMT-2'-OMe-U Structure

2'-O-Methyl-5'-...

CAS#:103285-22-9

Literature: ISIS Pharmaceuticals, Inc. Patent: US5914396 A1, 1999 ;

~90%

2'-O-Methyl-5'-O-DMT-Uridine;DMT-2'-OMe-U Structure

2'-O-Methyl-5'-...

CAS#:103285-22-9

Literature: Barbeyron, Renaud; Wengel, Jesper; Vasseur, Jean-Jacques; Smietana, Michael Monatshefte fur Chemie, 2013 , vol. 144, # 4 p. 495 - 500

~%

2'-O-Methyl-5'-O-DMT-Uridine;DMT-2'-OMe-U Structure

2'-O-Methyl-5'-...

CAS#:103285-22-9

Literature: Bioorganic and Medicinal Chemistry, , vol. 21, # 20 p. 6171 - 6180

~%

2'-O-Methyl-5'-O-DMT-Uridine;DMT-2'-OMe-U Structure

2'-O-Methyl-5'-...

CAS#:103285-22-9

Literature: Bioorganic and Medicinal Chemistry, , vol. 21, # 20 p. 6171 - 6180

 Synonyms

DMT-2'-OMe-U
5'-O-DMT-2'-O-METHYL-URIDINE
5'-DMT 2'-O-methyl uridine
2'-O-methyl-5"-O-dimethoxytrityl uridine
HG1364
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-uridine
2'-O-Methyl-5'-O-DMT-Uridine;DMT-2'-OMe-U