5'-Protected 2,2'-anhydrouridine

Modify Date: 2024-01-12 16:24:16

5'-Protected 2,2'-anhydrouridine Structure
5'-Protected 2,2'-anhydrouridine structure
Common Name 5'-Protected 2,2'-anhydrouridine
CAS Number 173170-12-2 Molecular Weight 528.55
Density N/A Boiling Point N/A
Molecular Formula C30H28N2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5'-Protected 2,2'-anhydrouridine


5'-Protected 2,2'-anhydrouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5'-DMTr-2,2'-anhydrouridine
Synonym More Synonyms

 5'-Protected 2,2'-anhydrouridine Biological Activity

Description 5'-Protected 2,2'-anhydrouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C30H28N2O7
Molecular Weight 528.55
Exact Mass 528.19000
PSA 101.27000
LogP 3.28850

 Synonyms

5'-O-(4,4'-dimethoxytrityl)-2,2'-O-anhydro-1-(β-D-arabinofuranosyl)uracil
2,2'-anhydro-5'-O-(4,4'-dimethoxytrityl)uridine
2,2'-O-anhydro-5'-O-(4,4'-dimethoxytrityl)(β-D-arabinofuranosyl)uracil
2,2'-O-anhydro-1-[5'-O-(4,4'-dimethoxytrityl)-β-D-arabinofuranosyl]uracil
5'-O-(4,4'-dimethoxytrityl)-2,2'-anhydrouridine
5'-O-dimethoxytrityl anhydrouridine
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