AS 2034178

Modify Date: 2025-08-24 23:40:34

AS 2034178 Structure
AS 2034178 structure
 Common Name AS 2034178
CAS Number 1030846-42-4 Molecular Weight 448.52900
Density 1.2±0.1 g/cm3 Boiling Point 657.9±55.0 °C at 760 mmHg
Molecular Formula C27H29FN2O3 Melting Point N/A
MSDS N/A Flash Point 351.7±31.5 °C

 Use of AS 2034178


AS2034178 free base, a specific and orally active GPR40 agonist, exhibits glucose-dependent insulin secretion enhancement. AS2034178 free base has potential for type 2 diabetes mellitus research[1].

 Names

Name 3-[2-Fluoro-4-({[1-(2-phenoxyethyl)-1,2,3,4-tetrahydro-5-quinolinyl]methyl}amino)phenyl]propanoic acid
Synonym More Synonyms

 AS 2034178 Biological Activity

Description AS2034178 free base, a specific and orally active GPR40 agonist, exhibits glucose-dependent insulin secretion enhancement. AS2034178 free base has potential for type 2 diabetes mellitus research[1].
Related Catalog
References

[1]. Tanaka H, et al. Chronic treatment with novel GPR40 agonists improve whole-body glucose metabolism based on the glucose-dependent insulin secretion. J Pharmacol Exp Ther. 2013;346(3):443-452.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 657.9±55.0 °C at 760 mmHg
Molecular Formula C27H29FN2O3
Molecular Weight 448.52900
Flash Point 351.7±31.5 °C
Exact Mass 448.21600
PSA 61.80000
LogP 5.44
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.622
InChIKey VENOXIKBBUVHRY-UHFFFAOYSA-N
SMILES O=C(O)CCc1ccc(NCc2cccc3c2CCCN3CCOc2ccccc2)cc1F

 Synonyms

Benzenepropanoic acid, 2-fluoro-4-[[[1,2,3,4-tetrahydro-1-(2-phenoxyethyl)-5-quinolinyl]methyl]amino]-
3-[2-Fluoro-4-({[1-(2-phenoxyethyl)-1,2,3,4-tetrahydro-5-quinolinyl]methyl}amino)phenyl]propanoic acid
AS2034178
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Chemsrc provides AS 2034178(CAS#:1030846-42-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of AS 2034178 are included as well.>> amp version: AS 2034178

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