Inositol 1,3,4,5-tetraphosphate

Modify Date: 2024-01-02 15:22:49

Inositol 1,3,4,5-tetraphosphate Structure
Inositol 1,3,4,5-tetraphosphate structure
Common Name Inositol 1,3,4,5-tetraphosphate
CAS Number 102850-29-3 Molecular Weight 517.10600
Density 2.32 g/cm3 Boiling Point 1015.6ºC at 760 mmHg
Molecular Formula C6H16O18P4 Melting Point N/A
MSDS USA Flash Point 568ºC

 Use of Inositol 1,3,4,5-tetraphosphate


Inositol 1,3,4,5-tetraphosphate is the head group of PIP3 (phosphatidylinositol 3,4,5-trisphosphate)[1].

 Names

Name d-myo-inositol 1,3,4,5-tetrakis-phosphate ammonium salt
Synonym More Synonyms

 Inositol 1,3,4,5-tetraphosphate Biological Activity

Description Inositol 1,3,4,5-tetraphosphate is the head group of PIP3 (phosphatidylinositol 3,4,5-trisphosphate)[1].
Related Catalog
References

[1]. Liu J, et al. Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation. J Biol Chem. 2011;286(50):43334-43342.

 Chemical & Physical Properties

Density 2.32 g/cm3
Boiling Point 1015.6ºC at 760 mmHg
Molecular Formula C6H16O18P4
Molecular Weight 517.10600
Flash Point 568ºC
Exact Mass 516.95500
PSA 349.98000
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.632

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles26

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IP3 3-kinase B controls hematopoietic stem cell homeostasis and prevents lethal hematopoietic failure in mice.

Blood 125 , 2786-97, (2015)

Tight regulation of hematopoietic stem cell (HSC) homeostasis ensures lifelong hematopoiesis and prevents blood cancers. The mechanisms balancing HSC quiescence with expansion and differentiation into...

Cell signaling. The art of the soluble.

Science 316(5826) , 845-6, (2007)

Interaction of the brain-specific protein p42IP4/centaurin-alpha1 with the peptidase nardilysin is regulated by the cognate ligands of p42IP4, PtdIns(3,4,5)P3 and Ins(1,3,4,5)P4, with stereospecificity.

J. Neurochem. 98(2) , 343-54, (2006)

The brain-specific protein p42IP4, also called centaurin-alpha1, specifically binds phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P3] and inositol 1,3,4,5-tetrakisphosphate [Ins(1,3,4,5)P4]. ...

 Synonyms

myo-inositol 1,3,4,5-tetrakisphosphate
INOSITOLTETRAPHOSPHATE
inositol-1,3,4,5-tetrakisphosphate
MYO-INOSITOL 1,3,4,6-TETRAKIS-PHOSPHATE AMMONIUM SALT
IP4
InsP4
D-myo-Inositol 1,3,4,5-tetrakisphosphoric acid
D-MYO-INOSITOL 1,3,4,5-TETRAKIS-*PHOSPHA TE AMMONIUM
Inositol 1,3,4,5-tetrakishosphate