Periglaucine A

Modify Date: 2024-01-14 11:45:42

Periglaucine A Structure
Periglaucine A structure
Common Name Periglaucine A
CAS Number 1025023-04-4 Molecular Weight 373.400
Density 1.4±0.1 g/cm3 Boiling Point 509.5±50.0 °C at 760 mmHg
Molecular Formula C20H23NO6 Melting Point N/A
MSDS N/A Flash Point 261.9±30.1 °C

 Use of Periglaucine A


Periglaucine A, a hasubanane-type alkaloid, can be isolated from Pericampylus glaucus. Periglaucine A can inhibits HBV surface antigen (HBsAg) secretion in Hep G2.2.15 cells. Periglaucine A also shows anti-HIV-1 activity in C8166 cells (EC50: 204 μM)[1].

 Names

Name (1S,11S,13S,14R,15R)-14,15-Dimethoxy-20-methyl-5,7,21-trioxa-20-azahexacyclo[11.4.3.111,14.01,13.02,10.04,8]henicosa-2(10),3,8-trien-16-one
Synonym More Synonyms

 Periglaucine A Biological Activity

Description Periglaucine A, a hasubanane-type alkaloid, can be isolated from Pericampylus glaucus. Periglaucine A can inhibits HBV surface antigen (HBsAg) secretion in Hep G2.2.15 cells. Periglaucine A also shows anti-HIV-1 activity in C8166 cells (EC50: 204 μM)[1].
Related Catalog
References

[1]. Yan MH, et al. Periglaucines A-D, anti-HBV and -HIV-1 alkaloids from Pericampylus glaucus. J Nat Prod. 2008 May;71(5):760-3.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 509.5±50.0 °C at 760 mmHg
Molecular Formula C20H23NO6
Molecular Weight 373.400
Flash Point 261.9±30.1 °C
Exact Mass 373.152527
PSA 66.46000
LogP 3.71
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.643

 Safety Information

Hazard Codes Xi

 Synonyms

4H,6H-3a,6-Methano-4,11b-propano-1H-[1,3]dioxolo[7,8][2]benzoxepino[4,5-b]pyrrol-13-one, 2,3-dihydro-4,14-dimethoxy-3-methyl-, (3aS,4R,6S,11bS,14R)-
periglaucine A
(1S,11S,13S,14R,15R)-14,15-Dimethoxy-20-methyl-5,7,21-trioxa-20-azahexacyclo[11.4.3.1.0.0.0]henicosa-2(10),3,8-trien-16-one
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