Atractyloside potassium salt

Modify Date: 2024-01-02 17:35:04

Atractyloside potassium salt Structure
Atractyloside potassium salt structure
Common Name Atractyloside potassium salt
CAS Number 102130-43-8 Molecular Weight 802.987
Density N/A Boiling Point N/A
Molecular Formula C30H44K2O16S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Atractyloside potassium salt


Atractyloside potassium salt is a toxic diterpenoid glycoside isolated from the fruits of Xanthium sibiricum. Atractyloside potassium salt is a powerful and specific inhibitor of mitochondrial ADP/ATP transport. Atractyloside potassium salt inhibits chloride channels from mitochondrial membranes of rat heart[1][2][3].

 Names

Name atractyloside potassium salt
Synonym More Synonyms

 Atractyloside potassium salt Biological Activity

Description Atractyloside potassium salt is a toxic diterpenoid glycoside isolated from the fruits of Xanthium sibiricum. Atractyloside potassium salt is a powerful and specific inhibitor of mitochondrial ADP/ATP transport. Atractyloside potassium salt inhibits chloride channels from mitochondrial membranes of rat heart[1][2][3].
Related Catalog
References

[1]. Nikles S, et al. Influence of Processing on the Content of Toxic Carboxyatractyloside and Atractyloside and the Microbiological Status of Xanthium sibiricum Fruits (Cang'erzi). Planta Med. 2015 Aug;81(12-13):1213-20.

[2]. Lemasters JJ, et al. Phosphate dependence and atractyloside inhibition of mitochondrial oxidative phosphorylation. The ADP-ATP carrier is rate-limiting. J Biol Chem. 1979 Feb 25;254(4):1248-51.

[3]. Malekova L, et al. Bongkrekic acid and atractyloside inhibits chloride channels from mitochondrial membranes of rat heart. Biochim Biophys Acta. 2007 Jan;1767(1):31-44.

 Chemical & Physical Properties

Molecular Formula C30H44K2O16S2
Molecular Weight 802.987
Exact Mass 802.134460
PSA 272.14000
LogP 3.14340
Storage condition 2-8°C

 Safety Information

Hazard Codes T: Toxic;
Risk Phrases R23/24/25
Safety Phrases S36/37
RIDADR UN 2811 6.1/PG 2
Hazard Class 6.1(a)

 Synonyms

ATRACTYLOSIDE,DIPOTASSIUM SALT,ATRACTYLIS GUMMIFERA
Atractyloside Dipotassium Salt
ATR,2K
Dipotassium (1R,4R,5R,7R,9R,10S,13R,15S)-5-carboxy-15-hydroxy-9-methyl-14-methylenetetracyclo[11.2.1.0.0]hexadec-7-yl 2-O-(3-methylbutanoyl)-3,4-di-O-sulfonato-α-D-glucopyranoside
MFCD00078810
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