3-Pyridinecarboxylicacid, 5-phenyl-

Modify Date: 2025-09-28 18:59:29

3-Pyridinecarboxylicacid, 5-phenyl- Structure
3-Pyridinecarboxylicacid, 5-phenyl- structure
Common Name 3-Pyridinecarboxylicacid, 5-phenyl-
CAS Number 10177-12-5 Molecular Weight 199.20500
Density 1.241g/cm3 Boiling Point 420.1ºC at 760mmHg
Molecular Formula C12H9NO2 Melting Point 260ºC
MSDS Chinese USA Flash Point 207.8ºC

 Names

Name 5-Phenylnicotinic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.241g/cm3
Boiling Point 420.1ºC at 760mmHg
Melting Point 260ºC
Molecular Formula C12H9NO2
Molecular Weight 199.20500
Flash Point 207.8ºC
Exact Mass 199.06300
PSA 50.19000
LogP 2.44680
Vapour Pressure 8.31E-08mmHg at 25°C
Index of Refraction 1.613

 MSDS

Name: 5-Phenylnicotinic acid 95+% Material Safety Data Sheet
Synonym:
CAS: 10177-12-5
Section 1 - Chemical Product MSDS Name:5-Phenylnicotinic acid 95+% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
10177-12-5 5-Phenylnicotinic acid 95+% unlisted
Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 10177-12-5: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 260 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C12H9NO2
Molecular Weight: 199.21

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Reducing agents, strong oxidizing agents, bases, amines.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 10177-12-5 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
5-Phenylnicotinic acid - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 10177-12-5: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 10177-12-5 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 10177-12-5 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xi: Irritant;
HS Code 2933399090

 Synthetic Route

~69%

3-Pyridinecarboxylicacid, 5-phenyl- Structure

3-Pyridinecarbo...

CAS#:10177-12-5

Literature: Carter, Percy H.; Cherney, Robert J.; Batt, Douglas G.; Brown, Gregory D.; Duncia, John V.; Gardner, Daniel S.; Yang, Michael G. Patent: US2005/54626 A1, 2005 ; Location in patent: Page/Page column 43 ; US 20050054626 A1

~79%

3-Pyridinecarboxylicacid, 5-phenyl- Structure

3-Pyridinecarbo...

CAS#:10177-12-5

Literature: Jain, Pooja; Slama, James T.; Perez-Haddock, Leroy A.; Walseth, Timothy F. Journal of Medicinal Chemistry, 2010 , vol. 53, # 21 p. 7599 - 7612

~%

3-Pyridinecarboxylicacid, 5-phenyl- Structure

3-Pyridinecarbo...

CAS#:10177-12-5

Literature: Journal of the American Chemical Society, , vol. 78, p. 3477,3481

~%

3-Pyridinecarboxylicacid, 5-phenyl- Structure

3-Pyridinecarbo...

CAS#:10177-12-5

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 17 p. 5498 - 5502

~%

3-Pyridinecarboxylicacid, 5-phenyl- Structure

3-Pyridinecarbo...

CAS#:10177-12-5

Literature: Tetrahedron Letters, , vol. 39, # 24 p. 4175 - 4178

~%

3-Pyridinecarboxylicacid, 5-phenyl- Structure

3-Pyridinecarbo...

CAS#:10177-12-5

Literature: Journal of the American Chemical Society, , vol. 78, p. 3477,3481

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

5-phenylpyridine-3-carboxylic acid
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