3-Pyridinecarboxylicacid, 5-phenyl

Modify Date: 2026-08-31 18:43:50

3-Pyridinecarboxylicacid, 5-phenyl Structure
3-Pyridinecarboxylicacid, 5-phenyl structure
Common Name 3-Pyridinecarboxylicacid, 5-phenyl
CAS Number 10177-12-5 Molecular Weight 199.20500
Density 1.241g/cm3 Boiling Point 420.1ºC at 760mmHg
Molecular Formula C12H9NO2 Melting Point 260ºC
MSDS Chinese USA Flash Point 207.8ºC

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 5-Phenylnicotinic acid
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.241g/cm3
Boiling Point 420.1ºC at 760mmHg
Melting Point 260ºC
Molecular Formula C12H9NO2
Molecular Weight 199.20500
Flash Point 207.8ºC
Exact Mass 199.06300
PSA 50.19000
LogP 2.44680
Vapour Pressure 8.31E-08mmHg at 25°C
Index of Refraction 1.613
InChIKey VKFXHYRIHRTEIV-UHFFFAOYSA-N
SMILES O=C(O)c1cncc(-c2ccccc2)c1

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Name: 5-Phenylnicotinic acid 95+% Material Safety Data Sheet
Synonym:
CAS: 10177-12-5
Section 1 - Chemical Product MSDS Name:5-Phenylnicotinic acid 95+% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
10177-12-5 5-Phenylnicotinic acid 95+% unlisted
Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 10177-12-5: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 260 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C12H9NO2
Molecular Weight: 199.21

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Reducing agents, strong oxidizing agents, bases, amines.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 10177-12-5 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
5-Phenylnicotinic acid - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 10177-12-5: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 10177-12-5 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 10177-12-5 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes Xi: Irritant;
HS Code 2933399090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

~69%

3-Pyridinecarboxylicacid, 5-phenyl Structure

3-Pyridinecarbo...

CAS#:10177-12-5

Learn More
Literature: Carter, Percy H.; Cherney, Robert J.; Batt, Douglas G.; Brown, Gregory D.; Duncia, John V.; Gardner, Daniel S.; Yang, Michael G. Patent: US2005/54626 A1, 2005 ; Location in patent: Page/Page column 43 ; US 20050054626 A1

~79%

3-Pyridinecarboxylicacid, 5-phenyl Structure

3-Pyridinecarbo...

CAS#:10177-12-5

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Literature: Jain, Pooja; Slama, James T.; Perez-Haddock, Leroy A.; Walseth, Timothy F. Journal of Medicinal Chemistry, 2010 , vol. 53, # 21 p. 7599 - 7612

~%

3-Pyridinecarboxylicacid, 5-phenyl Structure

3-Pyridinecarbo...

CAS#:10177-12-5

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Literature: Journal of the American Chemical Society, , vol. 78, p. 3477,3481

~%

3-Pyridinecarboxylicacid, 5-phenyl Structure

3-Pyridinecarbo...

CAS#:10177-12-5

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Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 17 p. 5498 - 5502

~%

3-Pyridinecarboxylicacid, 5-phenyl Structure

3-Pyridinecarbo...

CAS#:10177-12-5

Learn More
Literature: Tetrahedron Letters, , vol. 39, # 24 p. 4175 - 4178

~%

3-Pyridinecarboxylicacid, 5-phenyl Structure

3-Pyridinecarbo...

CAS#:10177-12-5

Learn More
Literature: Journal of the American Chemical Society, , vol. 78, p. 3477,3481

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  5

DownStream  0

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

5-phenylpyridine-3-carboxylic acid

 3-Pyridinecarboxylicacid, 5-phenyl | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the CAS number of 5-Phenylnicotinic acid?
A: CAS number of 5-Phenylnicotinic acid is 10177-12-5.
Q: What is the InChIKey of 5-Phenylnicotinic acid?
A: InChIKey of 5-Phenylnicotinic acid is VKFXHYRIHRTEIV-UHFFFAOYSA-N.
Q: What English synonyms does 5-Phenylnicotinic acid have?
A: English synonyms of 5-Phenylnicotinic acid: 5-phenylpyridine-3-carboxylic acid.
Q: What is the molecular formula of 5-Phenylnicotinic acid?
A: Molecular formula of 5-Phenylnicotinic acid is C12H9NO2.
Q: What is the melting point of 5-Phenylnicotinic acid?
A: Melting point of 5-Phenylnicotinic acid is 260ºC.
Q: What is the polar surface area (PSA) of 5-Phenylnicotinic acid?
A: Polar surface area (PSA) of 5-Phenylnicotinic acid is 50.19000.
Q: What is the molecular weight of 5-Phenylnicotinic acid?
A: Molecular weight of 5-Phenylnicotinic acid is 199.20500.
Q: What are the upstream materials of 5-Phenylnicotinic acid?
A: Related upstream materials(CAS) of 5-Phenylnicotinic acid: 20826-04-4;98-80-6;10477-94-8;122-78-1;960-16-7.
Q: What is the English name of 5-Phenylnicotinic acid?
A: The English name of 5-Phenylnicotinic acid is 5-Phenylnicotinic acid.
Q: What is the boiling point of 5-Phenylnicotinic acid?
A: Boiling point of 5-Phenylnicotinic acid is 420.1ºC at 760mmHg.

 3-Pyridinecarboxylicacid, 5-phenylfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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