5-[(3-{[(4R)-6,8-Dibromo-3,4-dihydro-2H-chromen-4-yl]amino}propyl )amino]thieno[3,2-b]pyridin-7(4H)-one dihydrochloride

Modify Date: 2025-08-25 15:45:50

5-[(3-{[(4R)-6,8-Dibromo-3,4-dihydro-2H-chromen-4-yl]amino}propyl )amino]thieno[3,2-b]pyridin-7(4H)-one dihydrochloride structure	Common Name	5-[(3-{[(4R)-6,8-Dibromo-3,4-dihydro-2H-chromen-4-yl]amino}propyl )amino]thieno[3,2-b]pyridin-7(4H)-one dihydrochloride
	CAS Number	1013915-99-5	Molecular Weight	586.16800
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₂₁Br₂Cl₂N₃O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 5-[(3-{[(4R)-6,8-Dibromo-3,4-dihydro-2H-chromen-4-yl]amino}propyl )amino]thieno[3,2-b]pyridin-7(4H)-one dihydrochloride

CRS3123 (REP-3123) dihydrochloride, a fully synthetic antibacterial agent, potently inhibits methionyl-tRNA synthetase (MetRS) of Clostridioides difficile, inhibiting Clostridioides difficile toxin production and spore formation. CRS3123 dihydrochloride is an oral agent for the research of Clostridioides difficile infection (CDI)[1].

Name	5-[(3-{[(4R)-6,8-Dibromo-3,4-dihydro-2H-chromen-4-yl]amino}propyl )amino]thieno[3,2-b]pyridin-7(4H)-one dihydrochloride

Description	CRS3123 (REP-3123) dihydrochloride, a fully synthetic antibacterial agent, potently inhibits methionyl-tRNA synthetase (MetRS) of Clostridioides difficile, inhibiting Clostridioides difficile toxin production and spore formation. CRS3123 dihydrochloride is an oral agent for the research of Clostridioides difficile infection (CDI)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Agent with Minimal Disruption of Normal Gut Microbiota. Antimicrob Agents Chemother. 2019 Dec 20;64(1):e01395-19.

Molecular Formula	C₁₉H₂₁Br₂Cl₂N₃O₂S
Molecular Weight	586.16800
Exact Mass	582.91000
PSA	97.88000
LogP	6.85910
InChIKey	HZJABMYSJSDCBO-FMOMHUKBSA-N
SMILES	Cl.Cl.O=c1cc(NCCCNC2CCOc3c(Br)cc(Br)cc32)[nH]c2ccsc12

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5-[(3-{[(4R)-6,8-Dibromo-3,4-dihydro-2H-chromen-4-yl]amino}propyl )amino]thieno[3,2-b]pyridin-7(4H)-one dihydrochloride

Use of 5-[(3-{[(4R)-6,8-Dibromo-3,4-dihydro-2H-chromen-4-yl]amino}propyl )amino]thieno[3,2-b]pyridin-7(4H)-one dihydrochloride

Names

Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.