sodium thiosulfate pentahydrate

Modify Date: 2024-01-02 17:56:25

sodium thiosulfate pentahydrate structure	Common Name	sodium thiosulfate pentahydrate
	CAS Number	10102-17-7	Molecular Weight	248.18400
	Density	1.01 g/mL at 25 °C	Boiling Point	100ºC
	Molecular Formula	H₁₀Na₂O₈S₂	Melting Point	48.5 °C
	MSDS	USA	Flash Point	N/A

Name	sodium thiosulfate pentahydrate
Synonym	More Synonyms

Density	1.01 g/mL at 25 °C
Boiling Point	100ºC
Melting Point	48.5 °C
Molecular Formula	H₁₀Na₂O₈S₂
Molecular Weight	248.18400
Exact Mass	247.96100
PSA	149.81000
LogP	0.18830
Stability	Stable. Incompatible with strong acids, iodine, mercury.
Water Solubility	680 g/L (20 ºC)

sodium thiosulfate pentahydrate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WE6660000

CHEMICAL NAME :: Sodium thiosulfate, pentahydrate

CAS REGISTRY NUMBER :: 10102-17-7

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: O3-S2.2Na.5H2-O

MOLECULAR WEIGHT :: 317.17

WISWESSER LINE NOTATION :: NA2 S2-O-Q2 QH5

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human

DOSE/DURATION :: 300 mg/kg/7D

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: TJEMAO Tohoku Journal of Experimental Medicine. (Maruzen Co. Ltd., Export Dept., P.O. Box 5050, Tokyo Int., 100-31 Tokyo, Japan) V.1- 1920- Volume(issue)/page/year: 63,383,1956

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 31,959,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 31,1713,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2350 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - other changes

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 13,89,1979

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Cardiac - pulse rate increase, without fall in BP Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: CNCRA6 Cancer Chemotherapy Reports. (Bethesda, MD) V.1-52, 1959-68. For publisher information, see CTRRDO. Volume(issue)/page/year: 50,255,1966 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1294 No. of Facilities: 358 (estimated) No. of Industries: 10 No. of Occupations: 12 No. of Employees: 3894 (estimated) No. of Female Employees: 2457 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	WE6660000
HS Code	28323000

HS Code	28323000

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Sodium thiosulfate pentahydrate

EINECS 231-867-5

MFCD00149186

disodium,dioxido-oxo-sulfanylidene-λ<sup>6</sup>-sulfane,pentahydrate