Metronidazole acetic acid
Metronidazole acetic acid structure
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Common Name | Metronidazole acetic acid | ||
|---|---|---|---|---|
| CAS Number | 1010-93-1 | Molecular Weight | 185.13700 | |
| Density | 1.6g/cm3 | Boiling Point | 475.9ºC at 760mmHg | |
| Molecular Formula | C6H7N3O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 241.6ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Metronidazole acetic acidMetronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa[1][2][3]. |
| Name | 2-(2-methyl-5-nitroimidazol-1-yl)acetic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa[1][2][3]. |
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| Related Catalog | |
| References |
| Density | 1.6g/cm3 |
|---|---|
| Boiling Point | 475.9ºC at 760mmHg |
| Molecular Formula | C6H7N3O4 |
| Molecular Weight | 185.13700 |
| Flash Point | 241.6ºC |
| Exact Mass | 185.04400 |
| PSA | 100.94000 |
| LogP | 0.70750 |
| Vapour Pressure | 7.28E-10mmHg at 25°C |
| Index of Refraction | 1.646 |
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~62%
Metronidazole a... CAS#:1010-93-1 |
| Literature: Journal of Heterocyclic Chemistry, , vol. 45, # 3 p. 921 - 925 |
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~13%
Metronidazole a... CAS#:1010-93-1 |
| Literature: WO2014/7650 A1, ; Page/Page column 54; 55 ; |
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~%
Metronidazole a... CAS#:1010-93-1 |
| Literature: European Journal of Medicinal Chemistry, , vol. 45, # 2 p. 661 - 666 |
| HS Code | 2933290090 |
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| Summary | 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Optimized liquid-chromatographic determination of metronidazole and its metabolites in plasma.
Clin. Chem. 30(5) , 784-7, (1984) Metronidazole and its known metabolites in plasma can be rapidly separated by a "high-pressure" liquid-chromatographic method that can also be adapted for rapid determination of tinidazole. Samples de... |
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Steady-state pharmacokinetics of metronidazole in Crohn's disease.
Biopharm. Drug Dispos. 8(3) , 249-59, (1987) The pharmacokinetics of metronidazole (MTZ) were studied in six Crohn's disease patients after multiple oral daily doses of 250, 500, 750, and 1000 mg day-1. Pharmacokinetic indices were found to be i... |
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Relative susceptibilities of Gardnerella vaginalis (Haemophilus vaginalis), Neisseria gonorrhoeae, and Bacteroides fragilis to Metronidazole and its two major metabolites.
Sex. Transm. Dis. 7(4) , 157-60, (1980) The susceptibilities of strains of Gardnerella vaginalis (Haemophilus vaginalis), Neisseria gonorrhoeae, and Bacteroides fragilis to metronidazole and its principal oxidative metabolites (1-[2-hydroxy... |
| 2-Methyl-5-nitro-1H-imidazole-1-acetic acid |
| 1-Carboxymethyl-2-methyl-5-nitro-imidazol |
| 2-methyl-5-nitroimidazole-1-acetic acid |
| Metronidazole acetic acid |