RTIL 13

Modify Date: 2025-08-27 14:14:20

RTIL 13 Structure
RTIL 13 structure
 Common Name RTIL 13
CAS Number 1009376-10-6 Molecular Weight 571.67
Density N/A Boiling Point N/A
Molecular Formula C30H55BrN2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RTIL 13


RTIL 13 is a potent inhibitor of dynamin GTPase, with an IC50 of 2.3 µM for dynamin I GTPase. RTIL 13 also targets pleckstrin homology lipid binding domain. RTIL 13 can inhibit receptor-mediated and synaptic vesicle endocytosis, with IC50s of 9.3 μM and 7.1 μM, respectively[1][2].

 Names

Name RTIL 13

 RTIL 13 Biological Activity

Description RTIL 13 is a potent inhibitor of dynamin GTPase, with an IC50 of 2.3 µM for dynamin I GTPase. RTIL 13 also targets pleckstrin homology lipid binding domain. RTIL 13 can inhibit receptor-mediated and synaptic vesicle endocytosis, with IC50s of 9.3 μM and 7.1 μM, respectively[1][2].
Related Catalog
Target

IC50: 2.3 µM (dynamin I GTPase)[1]

In Vitro RTIL 13 inhibits receptor-mediated and synaptic vesicle endocytosis, with IC50s of 9.3 μM and 7.1 μM, respectively[2].
References

[1]. Zhang J, et, al. From Spanish fly to room-temperature ionic liquids (RTILs): synthesis, thermal stability and inhibition of dynamin 1 GTPase by a novel class of RTILs. New Journal of Chemistry. 2008 Jan; 32(1): 1-180.

[2]. Ascent Scientific Launch Novel Dynamin Inhibitor Dyngo-4a™ with Children's Medical Research Institute and University of Newcastle. Tuesday, December 28, 2021.

 Chemical & Physical Properties

Molecular Formula C30H55BrN2O3
Molecular Weight 571.67
InChIKey NBQBCVMTAUPTCJ-PNXVFTDZSA-M
SMILES CCCCCCCCCCCCCCCCCC[N+](C)(C)CCN1C(=O)C2C3CCC(O3)C2C1=O.[Br-]

 Safety Information

Hazard Codes Xi
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Chemsrc provides RTIL 13(CAS#:1009376-10-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of RTIL 13 are included as well.>> amp version: RTIL 13

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