GSK1521498 free base (hydrochloride)

Modify Date: 2025-08-27 05:17:19

GSK1521498 free base (hydrochloride) structure	Common Name	GSK1521498 free base (hydrochloride)
	CAS Number	1007578-24-6	Molecular Weight	438.90
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₁ClF₂N₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of GSK1521498 free base (hydrochloride)

GSK1521498 free base (hydrochloride) is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 free base (hydrochloride) is being used for the treatment of disorders of compulsive consumption of food, alcohol, and drugs[1].

Name	GSK1521498 free base (hydrochloride)

Description	GSK1521498 free base (hydrochloride) is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 free base (hydrochloride) is being used for the treatment of disorders of compulsive consumption of food, alcohol, and drugs[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
Target	μ-opioid receptor[1]
References	[1]. Giuliano C, et al. The Novel μ-Opioid Receptor Antagonist GSK1521498 Decreases Both Alcohol Seeking and Drinking: Evidence from a New Preclinical Model of Alcohol Seeking. Neuropsychopharmacology. 2015 Dec;40(13):2981-92.

Molecular Formula	C₂₄H₂₁ClF₂N₄
Molecular Weight	438.90
InChIKey	GCHUHXBWBZOSOJ-UHFFFAOYSA-N
SMILES	Cl.Fc1cc(-c2cccc(-c3ncn[nH]3)c2)cc(F)c1CNC1Cc2ccccc2C1

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GSK1521498 free base (hydrochloride)

Use of GSK1521498 free base (hydrochloride)

Names

GSK1521498 free base (hydrochloride) Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.