diethyl 7-bromoheptylphosphonate

Modify Date: 2024-01-14 13:33:26

diethyl 7-bromoheptylphosphonate Structure
diethyl 7-bromoheptylphosphonate structure
Common Name diethyl 7-bromoheptylphosphonate
CAS Number 100462-73-5 Molecular Weight 315.18
Density N/A Boiling Point N/A
Molecular Formula C11H24BrO3P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of diethyl 7-bromoheptylphosphonate


Diethyl 7-bromoheptylphosphonate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Diethyl 7-bromoheptylphosphonate
Synonym More Synonyms

 diethyl 7-bromoheptylphosphonate Biological Activity

Description Diethyl 7-bromoheptylphosphonate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C11H24BrO3P
Molecular Weight 315.18

 Synonyms

MFCD24539457
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