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100462-73-5

100462-73-5 structure
100462-73-5 structure
  • Name: diethyl 7-bromoheptylphosphonate
  • Chemical Name: Diethyl 7-bromoheptylphosphonate
  • CAS Number: 100462-73-5
  • Molecular Formula: C11H24BrO3P
  • Molecular Weight: 315.18
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 09:09:28
  • Modify Date: 2024-01-14 13:33:26
  • Diethyl 7-bromoheptylphosphonate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Diethyl 7-bromoheptylphosphonate
Synonyms MFCD24539457
Description Diethyl 7-bromoheptylphosphonate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C11H24BrO3P
Molecular Weight 315.18
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