Tilapertin
Modify Date: 2025-08-21 18:08:50
Tilapertin structure
|
Common Name | Tilapertin | ||
|---|---|---|---|---|
| CAS Number | 1000690-85-6 | Molecular Weight | 378.388 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 455.3±45.0 °C at 760 mmHg | |
| Molecular Formula | C20H21F3N2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 229.2±28.7 °C | |
Use of TilapertinTilapertin is an oral inhibitor of glycine transporter type-1 (GlyT1). |
| Name | Tilapertin |
|---|---|
| Synonym | More Synonyms |
| Description | Tilapertin is an oral inhibitor of glycine transporter type-1 (GlyT1). |
|---|---|
| Related Catalog | |
| Target |
GlyT1[1] |
| In Vivo | Tilapertin is a nanomolar potent, orally bioavailable and selective GlyT1 inhibitor. Oral administration of Tilapertin dose-dependently increases cerebrospinal fluid (CSF) glycine concentration in rats[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 455.3±45.0 °C at 760 mmHg |
| Molecular Formula | C20H21F3N2O2 |
| Molecular Weight | 378.388 |
| Flash Point | 229.2±28.7 °C |
| Exact Mass | 378.155518 |
| LogP | 2.95 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.554 |
| InChIKey | MDLQJNCGZVDZFV-LJQANCHMSA-N |
| SMILES | O=C(O)CN1CCN(C(c2ccccc2)c2cccc(C(F)(F)F)c2)CC1 |
| Storage condition | 2-8℃ |
| (4-{(R)-Phenyl[3-(trifluoromethyl)phenyl]methyl}-1-piperazinyl)acetic acid |
| tilapertin |
| 1-Piperazineacetic acid, 4-[(R)-phenyl[3-(trifluoromethyl)phenyl]methyl]- |
| A2SV488G98 |