Wurster's blue

Modify Date: 2025-08-27 13:55:29

Wurster's blue structure	Common Name	Wurster's blue
	CAS Number	100-22-1	Molecular Weight	164.25
	Density	1.0±0.1 g/cm3	Boiling Point	260.6±13.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₁₆N₂	Melting Point	49-51 °C(lit.)
	MSDS	USA	Flash Point	104.9±7.7 °C
	Symbol	GHS07	Signal Word	Warning

Use of Wurster's blue

N,N,N′,N′-Tetramethyl-p-phenylenediamine (TMPD) is an redox indicator. N,N,N′,N′-Tetramethyl-p-phenylenediamine can be used for the research of impairment of cell respiration[1][2].

Name	N,N,N',N'-Tetramethyl-1,4-phenylenediamine
Synonym	More Synonyms

Description	N,N,N′,N′-Tetramethyl-p-phenylenediamine (TMPD) is an redox indicator. N,N,N′,N′-Tetramethyl-p-phenylenediamine can be used for the research of impairment of cell respiration[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Zhou S, Yao Y, et al. A cytochrome c-enhanced peroxidation reaction with potential use in screening dietary antioxidants. J Pharm Biomed Anal. 2004 Mar 10;34(5):1057-61. [2]. Sarti P, et al. Permeability of rat heart myocytes to cytochrome c. Cell Mol Life Sci. 1999 Dec;56(11-12):1061-9.

Description

N,N,N′,N′-Tetramethyl-p-phenylenediamine (TMPD) is an redox indicator. N,N,N′,N′-Tetramethyl-p-phenylenediamine can be used for the research of impairment of cell respiration[1][2].

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

References

[1]. Zhou S, Yao Y, et al. A cytochrome c-enhanced peroxidation reaction with potential use in screening dietary antioxidants. J Pharm Biomed Anal. 2004 Mar 10;34(5):1057-61.

[2]. Sarti P, et al. Permeability of rat heart myocytes to cytochrome c. Cell Mol Life Sci. 1999 Dec;56(11-12):1061-9.

Density	1.0±0.1 g/cm3
Boiling Point	260.6±13.0 °C at 760 mmHg
Melting Point	49-51 °C(lit.)
Molecular Formula	C₁₀H₁₆N₂
Molecular Weight	164.25
Flash Point	104.9±7.7 °C
Exact Mass	164.131348
PSA	6.48000
LogP	2.08
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.578
Stability	Stable, but may be air or light sensitive. Combustible. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.
Water Solubility	slightly in cold, more in hot water

Wurster's blue MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ST4200000

CHEMICAL NAME :: p-Phenylenediamine, N,N,N',N'-tetramethyl-

CAS REGISTRY NUMBER :: 100-22-1

LAST UPDATED :: 199701

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C10-H16-N2

MOLECULAR WEIGHT :: 164.28

WISWESSER LINE NOTATION :: 1N1&R DN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 780 mg/m3/10M

TOXIC EFFECTS :: Behavioral - irritability Lungs, Thorax, or Respiration - acute pulmonary edema

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: 42 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - wild bird species

DOSE/DURATION :: 23700 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 10 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 241,175,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3675 No. of Facilities: 14 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 232 (estimated) No. of Female Employees: 130 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H312-H332
Precautionary Statements	P280
Hazard Codes	Xn:Harmful;
Risk Phrases	R20/21/22
Safety Phrases	S28-S28A
RIDADR	UN 2811 6.1/PG 3
WGK Germany	1
RTECS	ST4200000
Packaging Group	II
Hazard Class	6.1(a)
HS Code	2921519090

Precursor 8
CAS#:100-25-4 P-DINITROBENZENE CAS#:50-00-0 Formaldehyde CAS#:106-50-3 p-Phenylenediamine CAS#:67-68-5 Dimethyl sulfoxide
CAS#:100-22-1 Wurster's blue CAS#:67-56-1 Methanol CAS#:624-18-0 Benzene-1,4-dia... CAS#:536-46-9 p-Dimethylamino...
DownStream 10
CAS#:100-22-1 Wurster's blue CAS#:99-98-9 N,N-Dimethyl-1,... CAS#:34527-56-5 N,N,N',N'-tetra... CAS#:603-33-8 Triphenylbismuth
CAS#:108805-98-7 2-phenyl-N,N,N'... CAS#:95-54-5 o-Phenylenediamine CAS#:198-55-0 perylene CAS#:1953-54-4 5-Indolol
CAS#:637-01-4 TMPD dihydrochloride CAS#:24624-25-7 tetra-N-methyl-...

HS Code	2921519090
Summary	2921519090. o-, m-, p-phenylenediamine, diaminotoluenes, and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:17.0%. . MFN tariff:6.5%. General tariff:30.0%

Cation binding site of cytochrome c oxidase: progress report.

Biochim. Biophys. Acta 1837(7) , 1188-95, (2014)

Cytochrome c oxidase from bovine heart binds Ca(2+) reversibly at a specific Cation Binding Site located near the outer face of the mitochondrial membrane. Ca(2+) shifts the absorption spectrum of hem...

Re-evaluation of the near infrared spectra of mitochondrial cytochrome c oxidase: Implications for non invasive in vivo monitoring of tissues.

Biochim. Biophys. Acta 1837(11) , 1882-91, (2014)

We re-determined the near infrared (NIR) spectral signatures (650-980nm) of the different cytochrome c oxidase redox centres, in the process separating them into their component species. We confirm th...

Synthesis, characterization, evaluation and molecular dynamics studies of 5, 6-diphenyl-1,2,4-triazin-3(2H)-one derivatives bearing 5-substituted 1,3,4-oxadiazole as potential anti-inflammatory and analgesic agents.

Eur. J. Med. Chem. 101 , 81-95, (2015)

A series of triazin-3(2H)-one derivatives bearing 1,3,4-oxadiazole (4a-4o) were synthesized, characterized and evaluated for anti-inflammatory and analgesic activities. Preliminary in vitro anti-infla...

1,4-Benzenediamine, N,N,N,N-tetramethyl-

tetramethylphenylenediamine

Wurster's blue

N,N,N′,N′-tetramethyl-p-phenylenediamine

EINECS 202-831-6

N,N,N‘,N‘-Tetramethyl-p-phenylenediamine

N,N,N',N'-Tetramethyl-1,4-benzenediamine

N,N,N′,N′-tetramethyl-para-phenylenediamine

1-N,1-N,4-N,4-N-tetramethylbenzene-1,4-diamine

N,N,N′,N′-Tetramethyl-1,4-phenylenediamine

MFCD00008309

n,n,n',n'-tetramethyl-p-phenylenediamine

N,N,N',N'-tetramethylbenzene-1,4-diamine

N,N,N,N-Tetramethyl-p-phenylenediamine

1,4-bis(dimethylamino)benzene

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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N,N,N',N'-Tetramethyl-1,4-phenylenediamine
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Purity: 98.0%
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: 100-22-1 C10H16N2 N,N,N',N'-Tetramethyl-1,4-phenylenediamine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
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Contact: Anson
Email: info@tianfuchem.com

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Wurster's blue

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CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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